U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Utp11 UTP11 small subunit processome component [ Mus musculus (house mouse) ]

Gene ID: 67205, updated on 3-Apr-2024

Summary

Go to the top of the page Help
Official Symbol
Utp11provided by MGI
Official Full Name
UTP11 small subunit processome componentprovided by MGI
Primary source
MGI:MGI:1914455
See related
Ensembl:ENSMUSG00000028907 AllianceGenome:MGI:1914455
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Cgi94; CGI-94; Utp11l; 2700082D03Rik
Summary
Predicted to be involved in nervous system development and positive regulation of apoptotic process. Predicted to be located in cytoplasm and extracellular space. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Is expressed in trigeminal ganglion and vertebral axis musculature. Orthologous to human UTP11 (UTP11 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 16.5), placenta adult (RPKM 13.4) and 23 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
4 D2.2; 4 57.87 cM
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (124571173..124587395, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (124678232..124693610, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene POU domain, class 3, transcription factor 1 Neighboring gene predicted gene, 38545 Neighboring gene STARR-positive B cell enhancer ABC_E6213 Neighboring gene four and a half LIM domains 3 Neighboring gene STARR-seq mESC enhancer starr_11340 Neighboring gene STARR-positive B cell enhancer ABC_E6214 Neighboring gene splicing factor 3a, subunit 3 Neighboring gene PRELI domain containing 1 pseudogene

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  2. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in nervous system development ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
probable U3 small nucleolar RNA-associated protein 11
Names
U3 snoRNA-associated protein 11
UTP11-like protein
UTP11-like, U3 small nucleolar ribonucleoprotein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001419148.1 → NP_001406077.1  probable U3 small nucleolar RNA-associated protein 11 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL606907

  2. NM_001419149.1 → NP_001406078.1  probable U3 small nucleolar RNA-associated protein 11 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL606907

  3. NM_026031.4 → NP_080307.1  probable U3 small nucleolar RNA-associated protein 11 isoform a

    See identical proteins and their annotated locations for NP_080307.1

    Status: VALIDATED

    Source sequence(s)
    AL606907
    Consensus CDS
    CCDS18623.1
    UniProtKB/Swiss-Prot
    Q3UI21, Q9CVB5, Q9CZJ1
    Related
    ENSMUSP00000030738.8, ENSMUST00000030738.8
    Conserved Domains (1) summary
    pfam03998
    Location:13 → 253
    Utp11; Utp11 protein

RNA

  1. NR_185021.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL606907

  2. NR_185022.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL606907

  3. NR_185023.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL606907

  4. NR_185024.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL606907

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    124571173..124587395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164362.1 → XP_036020255.1  probable U3 small nucleolar RNA-associated protein 11 isoform X2

    Conserved Domains (1) summary
    pfam03998
    Location:5 → 144
    Utp11; Utp11 protein

  2. XM_011240592.4 → XP_011238894.1  probable U3 small nucleolar RNA-associated protein 11 isoform X1

    UniProtKB/TrEMBL
    Q9D948
    Conserved Domains (1) summary
    pfam03998
    Location:1 → 184
    Utp11; Utp11 protein
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CZJ1.1 GenPept UniProtKB/Swiss-Prot:Q9CZJ1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous