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Ccdc25 coiled-coil domain containing 25 [ Mus musculus (house mouse) ]

Gene ID: 67179, updated on 5-Mar-2024

Summary

Official Symbol
Ccdc25provided by MGI
Official Full Name
coiled-coil domain containing 25provided by MGI
Primary source
MGI:MGI:1914429
See related
Ensembl:ENSMUSG00000022035 AllianceGenome:MGI:1914429
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NSrp70; 2610528H13Rik
Summary
Predicted to enable DNA binding activity. Predicted to be involved in positive regulation of cell motility. Predicted to be located in endomembrane system. Predicted to be integral component of plasma membrane. Orthologous to human CCDC25 (coiled-coil domain containing 25). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 9.9), CNS E11.5 (RPKM 9.8) and 27 other tissues See more
Orthologs
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Genomic context

See Ccdc25 in Genome Data Viewer
Location:
14 D1; 14 34.36 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (66074751..66104053)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (65837302..65866604)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:66424601-66424784 Neighboring gene PDZ binding kinase Neighboring gene STARR-seq mESC enhancer starr_36982 Neighboring gene STARR-seq mESC enhancer starr_36983 Neighboring gene establishment of sister chromatid cohesion N-acetyltransferase 2 Neighboring gene STARR-positive B cell enhancer ABC_E5449 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:66503658-66503811 Neighboring gene predicted gene, 41181 Neighboring gene predicted gene, 41182 Neighboring gene scavenger receptor class A, member 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Markers

Clone Names

  • MGC38132

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in positive regulation of cell motility ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endomembrane system ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145944.5NP_666056.1  coiled-coil domain-containing protein 25

    See identical proteins and their annotated locations for NP_666056.1

    Status: VALIDATED

    Source sequence(s)
    AC125058
    Consensus CDS
    CCDS27217.1
    UniProtKB/Swiss-Prot
    Q78PG9, Q9CSQ8, Q9CUF8
    UniProtKB/TrEMBL
    A0PK78
    Related
    ENSMUSP00000022614.6, ENSMUST00000022614.7
    Conserved Domains (1) summary
    pfam05670
    Location:1112
    DUF814; Domain of unknown function (DUF814)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    66074751..66104053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)