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Naa16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit [ Mus musculus (house mouse) ]

Gene ID: 66897, updated on 5-Mar-2024

Summary

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Official Symbol
Naa16provided by MGI
Official Full Name
N(alpha)-acetyltransferase 16, NatA auxiliary subunitprovided by MGI
Primary source
MGI:MGI:1914147
See related
Ensembl:ENSMUSG00000022020 AllianceGenome:MGI:1914147
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Narg1l; 1300019C06Rik
Summary
Predicted to enable ribosome binding activity. Predicted to contribute to peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal peptidyl-methionine acetylation; negative regulation of apoptotic process; and protein stabilization. Predicted to be located in cytosol. Predicted to be part of NatA complex. Predicted to be active in cytoplasm. Orthologous to human NAA16 (N-alpha-acetyltransferase 16, NatA auxiliary subunit). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 3.8), liver E14 (RPKM 3.7) and 26 other tissues See more
Orthologs
human all
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Genomic context

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Location:
14 D3; 14 42.61 cM
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (79571947..79628228, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (79334507..79390788, complement)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 957 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:79643421-79643608 Neighboring gene STARR-seq mESC enhancer starr_37253 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:79667780-79667981 Neighboring gene STARR-seq mESC enhancer starr_37256 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:79680321-79680522 Neighboring gene STARR-seq mESC enhancer starr_37257 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:79691968-79692228 Neighboring gene CapStarr-seq enhancer MGSCv37_chr14:79693274-79693461 Neighboring gene regulator of cell cycle Neighboring gene STARR-positive B cell enhancer ABC_E11576 Neighboring gene STARR-positive B cell enhancer ABC_E4121 Neighboring gene STARR-positive B cell enhancer ABC_E7342 Neighboring gene STARR-positive B cell enhancer ABC_E7343 Neighboring gene STARR-positive B cell enhancer ABC_E4122 Neighboring gene mitochondrial translational release factor 1 Neighboring gene kelch repeat and BTB (POZ) domain containing 7 Neighboring gene STARR-positive B cell enhancer ABC_E2429 Neighboring gene kelch repeat and BTB (POZ) domain containing 6

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Genetic, morphometric, and behavioral factors linked to the midsagittal area of the corpus callosum. Newbury AJ, et al. Front Genet, 2012. PMID 22666227, Free PMC Article
  2. An evolutionarily conserved N-terminal acetyltransferase complex associated with neuronal development. Sugiura N, et al. J Biol Chem, 2003 Oct 10. PMID 12888564
  3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables ribosome binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in N-terminal peptidyl-methionine acetylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in N-terminal protein amino acid acetylation ISO
Inferred from Sequence Orthology
more info
  
involved_in negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of NatA complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of NatA complex ISO
Inferred from Sequence Orthology
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
N-alpha-acetyltransferase 16, NatA auxiliary subunit
Names
NARG1-like protein
NMDA receptor-regulated 1-like protein
Nalpha acetyltransferase 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025832.2 → NP_080108.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit

    See identical proteins and their annotated locations for NP_080108.1

    Status: PROVISIONAL

    Source sequence(s)
    BC052445
    Consensus CDS
    CCDS27296.1
    UniProtKB/Swiss-Prot
    Q3U7V2, Q9DBB4
    Related
    ENSMUSP00000022597.8, ENSMUST00000022597.15
    Conserved Domains (4) summary
    sd00006
    Location:82 → 108
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:87 → 113
    TPR_1; Tetratricopeptide repeat
    pfam12569
    Location:187 → 698
    NARP1; NMDA receptor-regulated protein 1
    pfam13414
    Location:82 → 145
    TPR_11; TPR repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    79571947..79628228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006519399.2 → XP_006519462.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1

    Conserved Domains (2) summary
    sd00006
    Location:246 → 270
    TPR; TPR repeat [structural motif]
    pfam12569
    Location:55 → 566
    NARP1; NMDA receptor-regulated protein 1

  2. XM_030247958.1 → XP_030103818.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X2

    Conserved Domains (1) summary
    pfam12569
    Location:1 → 286
    NARP1; NMDA receptor-regulated protein 1

RNA

  1. XR_004938440.1 RNA Sequence

  2. XR_001781144.2 RNA Sequence

  3. XR_001781145.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DBB4.1 GenPept UniProtKB/Swiss-Prot:Q9DBB4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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