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Zfp507 zinc finger protein 507 [ Mus musculus (house mouse) ]

Gene ID: 668501, updated on 5-Mar-2024

Summary

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Official Symbol
Zfp507provided by MGI
Official Full Name
zinc finger protein 507provided by MGI
Primary source
MGI:MGI:1916378
See related
Ensembl:ENSMUSG00000044452 AllianceGenome:MGI:1916378
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm480; Znf507; mKIAA1084; 1810022O10Rik; A230056M16Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZNF507 (zinc finger protein 507). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 7.0), CNS E11.5 (RPKM 6.6) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
7 B2; 7 21.37 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (35471768..35502749, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (35772343..35803000, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42379 Neighboring gene dpy-19 like C-mannosyltransferase 3 Neighboring gene STARR-seq mESC enhancer starr_18641 Neighboring gene RIKEN cDNA E130304I02 gene Neighboring gene predicted gene, 36234 Neighboring gene predicted gene, 38990

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  2. Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo. Harrison SM, et al. Development, 1995 Aug. PMID 7671812
  3. Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2003 Aug 31. PMID 14621295
  4. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  5. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
zinc finger protein 507

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177739.3 → NP_808407.2  zinc finger protein 507

    See identical proteins and their annotated locations for NP_808407.2

    Status: VALIDATED

    Source sequence(s)
    AC120378, AK129283, AK142141, BE994250
    Consensus CDS
    CCDS52204.1
    UniProtKB/Swiss-Prot
    Q3UQU3, Q6ZPY5, Q80VK1
    Related
    ENSMUSP00000058609.5, ENSMUST00000061586.11
    Conserved Domains (1) summary
    sd00017
    Location:632 → 652
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    35471768..35502749 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242902.2 → XP_030098762.1  zinc finger protein 507 isoform X1

    UniProtKB/Swiss-Prot
    Q3UQU3, Q6ZPY5, Q80VK1
    Conserved Domains (1) summary
    sd00017
    Location:632 → 652
    ZF_C2H2; C2H2 Zn finger [structural motif]

  2. XM_006540298.3 → XP_006540361.1  zinc finger protein 507 isoform X2

    Conserved Domains (2) summary
    smart00355
    Location:596 → 618
    ZnF_C2H2; zinc finger
    sd00017
    Location:570 → 590
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6ZPY5.2 GenPept UniProtKB/Swiss-Prot:Q6ZPY5

Gene LinkOut

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