U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Mrpl33 mitochondrial ribosomal protein L33 [ Mus musculus (house mouse) ]

Gene ID: 66845, updated on 5-Mar-2024

Summary

Official Symbol
Mrpl33provided by MGI
Official Full Name
mitochondrial ribosomal protein L33provided by MGI
Primary source
MGI:MGI:2137225
See related
Ensembl:ENSMUSG00000106918 AllianceGenome:MGI:2137225
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
L33mt; MRP-L33; 0610009M10Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including brain; early conceptus; endocrine gland; genitourinary system; and liver. Orthologous to human MRPL33 (mitochondrial ribosomal protein L33). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 49.5), bladder adult (RPKM 44.4) and 21 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
5 B1; 5 17.27 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (31771295..31779988)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (31613951..31622644)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:31829068-31829342 Neighboring gene solute carrier family 4 (anion exchanger), member 1, adaptor protein Neighboring gene STARR-seq mESC enhancer starr_12773 Neighboring gene expressed sequence AI839979 Neighboring gene STARR-seq mESC enhancer starr_12777 Neighboring gene STARR-positive B cell enhancer ABC_E4750 Neighboring gene STARR-seq mESC enhancer starr_12780 Neighboring gene STARR-seq mESC enhancer starr_12781 Neighboring gene predicted gene, 38424 Neighboring gene ribokinase Neighboring gene microRNA 3473e Neighboring gene STARR-positive B cell enhancer ABC_E11723 Neighboring gene BRISC and BRCA1 A complex member 2 Neighboring gene STARR-seq mESC enhancer starr_12782 Neighboring gene STARR-seq mESC enhancer starr_12783 Neighboring gene STARR-seq mESC enhancer starr_12784 Neighboring gene predicted gene, 52770

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein bL33m
Names
39S ribosomal protein L33, mitochondrial
NP_080072.2

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025796.3NP_080072.2  large ribosomal subunit protein bL33m

    See identical proteins and their annotated locations for NP_080072.2

    Status: VALIDATED

    Source sequence(s)
    BC055724, BY112771
    Consensus CDS
    CCDS39056.1
    UniProtKB/Swiss-Prot
    Q9CQP0, Q9D860
    UniProtKB/TrEMBL
    Q8C9M6
    Related
    ENSMUSP00000031024.8, ENSMUST00000031024.14
    Conserved Domains (1) summary
    pfam00471
    Location:1660
    Ribosomal_L33; Ribosomal protein L33

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    31771295..31779988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)