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Zfp966 zinc finger protein 966 [ Mus musculus (house mouse) ]

Gene ID: 667962, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp966provided by MGI
Official Full Name
zinc finger protein 966provided by MGI
Primary source
MGI:MGI:3709288
See related
Ensembl:ENSMUSG00000089756 AllianceGenome:MGI:3709288
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm8898
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 4.9), cerebellum adult (RPKM 3.9) and 24 other tissues See more
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Genomic context

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Location:
2 H4; 2 98.74 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (175710076..175722893, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (175918283..175931100, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr2:175868122-175868422 Neighboring gene predicted gene 6710 Neighboring gene predicted gene, 42247 Neighboring gene predicted gene 2026 Neighboring gene zinc finger protein 717-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
KRAB box and zinc finger C2H2 type domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177405.1 → NP_001170876.1  KRAB box and zinc finger C2H2 type domain containing protein isoform 2

    See identical proteins and their annotated locations for NP_001170876.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal exon in the 5' region and an internal segment in the 3' region, as compared to variant 1. The resulting isoform (2) is shorter; it has a different C-terminus and lacks zinc finger C2H2 type domain, as compared to isoform 1.
    Source sequence(s)
    AL845476
    Consensus CDS
    CCDS50824.1
    UniProtKB/TrEMBL
    A2ART1
    Related
    ENSMUSP00000104646.3, ENSMUST00000109018.3

  2. NM_001177407.1 → NP_001170878.1  KRAB box and zinc finger C2H2 type domain containing protein isoform 1

    See identical proteins and their annotated locations for NP_001170878.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1) including KRAB box and zinc finger C2H2 type domain.
    Source sequence(s)
    AL845476
    Consensus CDS
    CCDS50825.1
    UniProtKB/TrEMBL
    A2ART2
    Related
    ENSMUSP00000104577.3, ENSMUST00000108949.3
    Conserved Domains (3) summary
    COG5048
    Location:94 → 478
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:208 → 228
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:22 → 63
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    175710076..175722893 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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