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Oser1 oxidative stress responsive serine rich 1 [ Mus musculus (house mouse) ]

Gene ID: 66680, updated on 3-Apr-2024

Summary

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Official Symbol
Oser1provided by MGI
Official Full Name
oxidative stress responsive serine rich 1provided by MGI
Primary source
MGI:MGI:1913930
See related
Ensembl:ENSMUSG00000035399 AllianceGenome:MGI:1913930
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Perit1; 3230401D17Rik
Summary
Predicted to be involved in cellular response to hydrogen peroxide. Is expressed in cerebral cortex ventricular layer. Orthologous to human OSER1 (oxidative stress responsive serine rich 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis adult (RPKM 70.1), placenta adult (RPKM 16.5) and 21 other tissues See more
Orthologs
human all
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Genomic context

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See Oser1 in Genome Data Viewer
Location:
2 H3; 2 84.26 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (163247742..163266422, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (163405822..163419470, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:163054873-163055132 Neighboring gene TOX high mobility group box family member 2 Neighboring gene VISTA enhancer mm1646 Neighboring gene junctophilin 2 Neighboring gene predicted gene, 35750 Neighboring gene STARR-seq mESC enhancer starr_06306 Neighboring gene STARR-seq mESC enhancer starr_06307 Neighboring gene STARR-positive B cell enhancer ABC_E2651 Neighboring gene RIKEN cDNA 2900093K20 gene Neighboring gene STARR-positive B cell enhancer ABC_E1608 Neighboring gene ganglioside-induced differentiation-associated protein 1-like 1 Neighboring gene STARR-seq mESC enhancer starr_06310 Neighboring gene RIKEN cDNA 2310001K24 gene Neighboring gene STARR-positive B cell enhancer ABC_E4516 Neighboring gene fat storage-inducing transmembrane protein 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cardiac myocyte gene expression profiling during H2O2-induced apoptosis. Clerk A, et al. Physiol Genomics, 2007 Apr 24. PMID 17148688
  2. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
  3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in cellular response to hydrogen peroxide IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in cellular response to hydrogen peroxide ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
oxidative stress-responsive serine-rich protein 1
Names
oxidative stress-responsive protein 1
peroxide-inducible transcript 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418537.1 → NP_001405466.1  oxidative stress-responsive serine-rich protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL589876
    UniProtKB/Swiss-Prot
    A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1
    Related
    ENSMUSP00000131932.2, ENSMUST00000104954.9

  2. NM_001418538.1 → NP_001405467.1  oxidative stress-responsive serine-rich protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL589876
    UniProtKB/Swiss-Prot
    A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1

  3. NM_001418539.1 → NP_001405468.1  oxidative stress-responsive serine-rich protein 1 isoform a

    Status: VALIDATED

    Source sequence(s)
    AL589876
    UniProtKB/Swiss-Prot
    A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1

  4. NM_001418540.1 → NP_001405469.1  oxidative stress-responsive serine-rich protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AL589876

  5. NM_025699.3 → NP_079975.2  oxidative stress-responsive serine-rich protein 1 isoform a

    See identical proteins and their annotated locations for NP_079975.2

    Status: VALIDATED

    Source sequence(s)
    AL589876
    Consensus CDS
    CCDS17009.1
    UniProtKB/Swiss-Prot
    A2A477, Q3U5N3, Q9CXJ2, Q9D722, Q9D9G1
    UniProtKB/TrEMBL
    Q3UT72
    Related
    ENSMUSP00000039190.4, ENSMUST00000046908.10
    Conserved Domains (1) summary
    pfam05604
    Location:1 → 175
    DUF776; Protein of unknown function (DUF776)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    163247742..163266422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D722.1 GenPept UniProtKB/Swiss-Prot:Q9D722

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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