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Msantd3 Myb/SANT-like DNA-binding domain containing 3 [ Mus musculus (house mouse) ]

Gene ID: 66665, updated on 5-Mar-2024

Summary

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Official Symbol
Msantd3provided by MGI
Official Full Name
Myb/SANT-like DNA-binding domain containing 3provided by MGI
Primary source
MGI:MGI:1913915
See related
Ensembl:ENSMUSG00000039693 AllianceGenome:MGI:1913915
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mysantd3; 2410046L14Rik; 2810429P03Rik; 5730528L13Rik
Summary
Orthologous to human MSANTD3 (Myb/SANT DNA binding domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 8.9), CNS E14 (RPKM 7.5) and 16 other tissues See more
Orthologs
human all
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Genomic context

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Location:
4 B1; 4 26.13 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (48539532..48565892)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (48539854..48565892)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene inversin Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene Neighboring gene testis expressed gene 10 Neighboring gene STARR-positive B cell enhancer ABC_E6178 Neighboring gene STARR-seq mESC enhancer starr_10161 Neighboring gene STARR-seq mESC enhancer starr_10162 Neighboring gene STARR-seq mESC enhancer starr_10163 Neighboring gene STARR-seq mESC enhancer starr_10164 Neighboring gene STARR-seq mESC enhancer starr_10167 Neighboring gene transmembrane protein with EGF-like and two follistatin-like domains 1 Neighboring gene caveolae associated 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Enhanced serotonin response in the hippocampus of Galphaz protein knock-out mice. Oleskevich S, et al. Neuroreport, 2005 Jun 21. PMID 15931062
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
myb/SANT-like DNA-binding domain-containing protein 3
Names
UPF0439 protein C9orf30 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145924.1 → NP_001139396.1  myb/SANT-like DNA-binding domain-containing protein 3

    See identical proteins and their annotated locations for NP_001139396.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All three transcripts encode the same protein.
    Source sequence(s)
    AK011381, AK017795, BC052696
    Consensus CDS
    CCDS18167.1
    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Related
    ENSMUSP00000065785.3, ENSMUST00000064807.9
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

  2. NM_001145925.1 → NP_001139397.1  myb/SANT-like DNA-binding domain-containing protein 3

    See identical proteins and their annotated locations for NP_001139397.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three transcripts encode the same protein.
    Source sequence(s)
    AK075956, BC052696
    Consensus CDS
    CCDS18167.1
    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Related
    ENSMUSP00000056551.2, ENSMUST00000061135.8
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

  3. NM_028137.3 → NP_082413.2  myb/SANT-like DNA-binding domain-containing protein 3

    See identical proteins and their annotated locations for NP_082413.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three transcripts encode the same protein.
    Source sequence(s)
    BC052696
    Consensus CDS
    CCDS18167.1
    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Related
    ENSMUSP00000103332.2, ENSMUST00000107704.2
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    48539532..48565892
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006538188.5 → XP_006538251.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006538251.1

    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

  2. XM_036164344.1 → XP_036020237.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

  3. XM_011250086.4 → XP_011248388.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011248388.1

    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

  4. XM_006538187.4 → XP_006538250.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006538250.1

    UniProtKB/Swiss-Prot
    Q9CR78, Q9CYY5
    Conserved Domains (1) summary
    pfam13873
    Location:10 → 87
    Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CR78.1 GenPept UniProtKB/Swiss-Prot:Q9CR78

Gene LinkOut

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