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Zfp991 zinc finger protein 991 [ Mus musculus (house mouse) ]

Gene ID: 666532, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp991provided by MGI
Official Full Name
zinc finger protein 991provided by MGI
Primary source
MGI:MGI:3701604
See related
Ensembl:ENSMUSG00000067916 AllianceGenome:MGI:3701604
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm13139
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in genitourinary system. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 5.2), testis adult (RPKM 4.8) and 19 other tissues See more
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Genomic context

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Location:
4 E1; 4 78.44 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (147198335..147266219)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (147132093..147180579)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 13160 Neighboring gene predicted gene 13142 Neighboring gene STARR-positive B cell enhancer mm9_chr4:145951820-145952121 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146498255-146498556 Neighboring gene vomeronasal 2, receptor, pseudogene 18 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146506000-146506300 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146516417-146516717 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146546713-146547013 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146548117-146548418 Neighboring gene STARR-positive B cell enhancer mm9_chr4:146549342-146549643 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3 pseudogene Neighboring gene 60S acidic ribosomal protein P1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  3. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC19361

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC666532
Names
novel KRAB box domain containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001083918.1 → NP_001077387.1  uncharacterized protein LOC666532

    See identical proteins and their annotated locations for NP_001077387.1

    Status: PREDICTED

    Source sequence(s)
    BC024323
    Consensus CDS
    CCDS38961.1
    UniProtKB/TrEMBL
    Q8R1N3
    Related
    ENSMUSP00000081167.4, ENSMUST00000084149.10
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    147198335..147266219
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164340.1 → XP_036020233.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  2. XM_036164329.1 → XP_036020222.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  3. XM_036164331.1 → XP_036020224.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  4. XM_036164333.1 → XP_036020226.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  5. XM_036164337.1 → XP_036020230.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  6. XM_036164328.1 → XP_036020221.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  7. XM_036164335.1 → XP_036020228.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  8. XM_036164330.1 → XP_036020223.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  9. XM_036164338.1 → XP_036020231.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  10. XM_036164334.1 → XP_036020227.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  11. XM_036164342.1 → XP_036020235.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  12. XM_036164323.1 → XP_036020216.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  13. XM_036164317.1 → XP_036020210.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  14. XM_036164322.1 → XP_036020215.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  15. XM_036164318.1 → XP_036020211.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  16. XM_036164324.1 → XP_036020217.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  17. XM_036164319.1 → XP_036020212.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  18. XM_036164325.1 → XP_036020218.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  19. XM_036164320.1 → XP_036020213.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  20. XM_036164326.1 → XP_036020219.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  21. XM_036164321.1 → XP_036020214.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  22. XM_036164327.1 → XP_036020220.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  23. XM_036164339.1 → XP_036020232.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  24. XM_036164332.1 → XP_036020225.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  25. XM_036164336.1 → XP_036020229.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  26. XM_036164343.1 → XP_036020236.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box

  27. XM_036164341.1 → XP_036020234.1  uncharacterized protein LOC666532 isoform X1

    UniProtKB/TrEMBL
    Q8R1N3
    Conserved Domains (3) summary
    COG5048
    Location:266 → 550
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:270 → 290
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:12 → 52
    KRAB; KRAB box
Nucleotide Protein Strain
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