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Cmc2 C-X9-C motif containing 2 [ Mus musculus (house mouse) ]

Gene ID: 66531, updated on 16-Apr-2024

Summary

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Official Symbol
Cmc2provided by MGI
Official Full Name
C-X9-C motif containing 2provided by MGI
Primary source
MGI:MGI:1913781
See related
Ensembl:ENSMUSG00000014633 AllianceGenome:MGI:1913781
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DC13; 1110046L09Rik; 2310061C15Rik
Summary
Predicted to be active in mitochondrion. Orthologous to human CMC2 (C-X9-C motif containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 8.3), heart adult (RPKM 7.9) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cmc2 in Genome Data Viewer
Location:
8 E1; 8 63.28 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (117615424..117671061, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (116888685..116944322, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene translation machinery-associated protein 7 pseudogene Neighboring gene predicted gene, 42045 Neighboring gene STARR-seq mESC enhancer starr_22803 Neighboring gene STARR-positive B cell enhancer ABC_E6690 Neighboring gene centromere protein N Neighboring gene ATM interactor Neighboring gene RIKEN cDNA 1700030J22 gene Neighboring gene STARR-positive B cell enhancer ABC_E2878 Neighboring gene STARR-positive B cell enhancer ABC_E6691 Neighboring gene STARR-positive B cell enhancer ABC_E3808 Neighboring gene glycine cleavage system protein H (aminomethyl carrier)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
  2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
  3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

See all (18) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
COX assembly mitochondrial protein 2 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026844.3 → NP_081120.2  COX assembly mitochondrial protein 2 homolog

    See identical proteins and their annotated locations for NP_081120.2

    Status: VALIDATED

    Source sequence(s)
    AC121101, AK002429
    Consensus CDS
    CCDS40489.1
    UniProtKB/Swiss-Prot
    Q8CEV6, Q8K199
    Related
    ENSMUSP00000120966.2, ENSMUST00000148235.8
    Conserved Domains (1) summary
    pfam08583
    Location:1 → 70
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    117615424..117671061 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006531282.3 → XP_006531345.1  COX assembly mitochondrial protein 2 homolog isoform X1

    See identical proteins and their annotated locations for XP_006531345.1

    UniProtKB/Swiss-Prot
    Q8CEV6, Q8K199
    Conserved Domains (1) summary
    pfam08583
    Location:1 → 70
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like

  2. XM_011248485.3 → XP_011246787.1  COX assembly mitochondrial protein 2 homolog isoform X1

    See identical proteins and their annotated locations for XP_011246787.1

    UniProtKB/Swiss-Prot
    Q8CEV6, Q8K199
    Conserved Domains (1) summary
    pfam08583
    Location:1 → 70
    Cmc1; Cytochrome c oxidase biogenesis protein Cmc1 like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K199.1 GenPept UniProtKB/Swiss-Prot:Q8K199

Gene LinkOut

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