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Mrps21 mitochondrial ribosomal protein S21 [ Mus musculus (house mouse) ]

Gene ID: 66292, updated on 5-Mar-2024

Summary

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Official Symbol
Mrps21provided by MGI
Official Full Name
mitochondrial ribosomal protein S21provided by MGI
Primary source
MGI:MGI:1913542
See related
Ensembl:ENSMUSG00000054312 AllianceGenome:MGI:1913542
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S21mt; 1810031B19Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrial inner membrane. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPS21 (mitochondrial ribosomal protein S21). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 59.5), CNS E11.5 (RPKM 58.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
3 F2.1; 3 41.36 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (95769946..95778826, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (95862634..95871514, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene regulation of nuclear pre-mRNA domain containing 2 Neighboring gene STARR-seq mESC enhancer starr_08396 Neighboring gene predicted gene, 29948 Neighboring gene pre-mRNA processing factor 3 Neighboring gene STARR-positive B cell enhancer ABC_E10199 Neighboring gene RIKEN cDNA C920021L13 gene Neighboring gene STARR-positive B cell enhancer ABC_E9562 Neighboring gene cDNA sequence BC028528 Neighboring gene circadian associated repressor of transcription Neighboring gene STARR-positive B cell enhancer ABC_E2673 Neighboring gene aph1 homolog A, gamma secretase subunit Neighboring gene carbonic anhydrase 14

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Mammalian mitochondrial ribosomal small subunit (MRPS) genes: A putative role in human disease. Gopisetty G, et al. Gene, 2016 Sep 1. PMID 27170550
  2. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
  3. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. Suzuki T, et al. J Biol Chem, 2001 Aug 31. PMID 11402041
  4. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  5. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein bS21m
Names
28S ribosomal protein S21, mitochondrial
NP_001342688.1
NP_510964.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355759.1 → NP_001342688.1  small ribosomal subunit protein bS21m

    Status: VALIDATED

    Source sequence(s)
    AC092855, AC093317, AK008265
    Consensus CDS
    CCDS38550.1
    UniProtKB/Swiss-Prot
    P58059
    UniProtKB/TrEMBL
    Q059G7
    Related
    ENSMUSP00000066990.5, ENSMUST00000067298.5
    Conserved Domains (1) summary
    TIGR00030
    Location:10 → 66
    S21p; ribosomal protein S21

  2. NM_078479.4 → NP_510964.1  small ribosomal subunit protein bS21m

    See identical proteins and their annotated locations for NP_510964.1

    Status: VALIDATED

    Source sequence(s)
    AC092855, AC093317, BC027546
    Consensus CDS
    CCDS38550.1
    UniProtKB/Swiss-Prot
    P58059
    UniProtKB/TrEMBL
    Q059G7
    Conserved Domains (1) summary
    TIGR00030
    Location:10 → 66
    S21p; ribosomal protein S21

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    95769946..95778826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P58059.1 GenPept UniProtKB/Swiss-Prot:P58059

Gene LinkOut

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