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Mrps17 mitochondrial ribosomal protein S17 [ Mus musculus (house mouse) ]

Gene ID: 66258, updated on 5-Mar-2024

Summary

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Official Symbol
Mrps17provided by MGI
Official Full Name
mitochondrial ribosomal protein S17provided by MGI
Primary source
MGI:MGI:1913508
See related
Ensembl:ENSMUSG00000034211 AllianceGenome:MGI:1913508
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mprs17; 1810006P02Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; liver; and sensory organ. Orthologous to human MRPS17 (mitochondrial ribosomal protein S17). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in limb E14.5 (RPKM 18.2), CNS E18 (RPKM 18.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Mrps17 in Genome Data Viewer
Location:
5 G1.3; 5 68.25 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (129792514..129795776)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (129715450..129718712)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 11 Neighboring gene septin 14 Neighboring gene STARR-seq mESC enhancer starr_14455 Neighboring gene STARR-positive B cell enhancer ABC_E11303 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:130230774-130230883 Neighboring gene nipsnap homolog 2 Neighboring gene STARR-seq mESC enhancer starr_14458 Neighboring gene STARR-seq mESC enhancer starr_14459 Neighboring gene phosphoserine phosphatase Neighboring gene STARR-positive B cell enhancer ABC_E854

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
  2. Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit. Suzuki T, et al. J Biol Chem, 2001 Aug 31. PMID 11402041
  3. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
  5. The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery. Baines K, et al. Autophagy Rep, 2022. PMID 35449600, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein uS17m
Names
28S ribosomal protein S17, mitochondrial
MRP-S17
S17mt

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356954.1 → NP_001343883.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  2. NM_001356955.1 → NP_001343884.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Related
    ENSMUSP00000112993.2, ENSMUST00000118420.8
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  3. NM_001356956.1 → NP_001343885.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Related
    ENSMUSP00000112779.2, ENSMUST00000119576.8
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  4. NM_001356957.1 → NP_001343886.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  5. NM_001356958.1 → NP_001343887.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  6. NM_001356959.1 → NP_001343888.1  small ribosomal subunit protein uS17m precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR compared to variant 1. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Related
    ENSMUSP00000040281.6, ENSMUST00000042191.12
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  7. NM_025450.5 → NP_079726.1  small ribosomal subunit protein uS17m precursor

    See identical proteins and their annotated locations for NP_079726.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. Variants 1-7 all encode the same protein.
    Source sequence(s)
    AC120413, AK007356
    Consensus CDS
    CCDS19697.1
    UniProtKB/Swiss-Prot
    Q9CQE3
    Related
    ENSMUSP00000114012.2, ENSMUST00000119604.8
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

RNA

  1. NR_151584.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks two alternate internal exons compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding region, including the translational start codon, found in variant 1.
    Source sequence(s)
    AC120413

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    129792514..129795776
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030254752.1 → XP_030110612.1  small ribosomal subunit protein uS17m isoform X1

    UniProtKB/Swiss-Prot
    Q9CQE3
    Related
    ENSMUSP00000114125.2, ENSMUST00000121339.2
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17

  2. XM_030254753.1 → XP_030110613.1  small ribosomal subunit protein uS17m isoform X1

    UniProtKB/Swiss-Prot
    Q9CQE3
    Conserved Domains (1) summary
    pfam00366
    Location:15 → 83
    Ribosomal_S17; Ribosomal protein S17
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQE3.1 GenPept UniProtKB/Swiss-Prot:Q9CQE3

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