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Ndufb9 NADH:ubiquinone oxidoreductase subunit B9 [ Mus musculus (house mouse) ]

Gene ID: 66218, updated on 9-Dec-2024

Summary

Official Symbol
Ndufb9provided by MGI
Official Full Name
NADH:ubiquinone oxidoreductase subunit B9provided by MGI
Primary source
MGI:MGI:1913468
See related
Ensembl:ENSMUSG00000022354 AllianceGenome:MGI:1913468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CI-B22; 1190008J14Rik
Summary
Predicted to be involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; integumental system; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 24. Orthologous to human NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Ubiquitous expression in heart adult (RPKM 349.2), kidney adult (RPKM 234.3) and 28 other tissues See more
Orthologs
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Genomic context

See Ndufb9 in Genome Data Viewer
Location:
15 D1; 15 25.09 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (58805650..58811365)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (58933801..58939516)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36509 Neighboring gene STARR-seq mESC enhancer starr_38762 Neighboring gene ring finger protein 139 Neighboring gene TatD DNase domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E8590 Neighboring gene MTSS I-BAR domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E8591 Neighboring gene RIKEN cDNA 4930544F09 gene Neighboring gene STARR-positive B cell enhancer ABC_E5481 Neighboring gene STARR-positive B cell enhancer ABC_E7370 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:58879422-58879623 Neighboring gene STARR-positive B cell enhancer ABC_E7371 Neighboring gene STARR-seq mESC enhancer starr_38772 Neighboring gene STARR-seq mESC enhancer starr_38774 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:58921314-58921561 Neighboring gene STARR-seq mESC enhancer starr_38776 Neighboring gene STARR-seq mESC enhancer starr_38777 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:58939028-58939233 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:59006027-59006221 Neighboring gene ribosomal protein L7, pseudogene 8

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Interactions

General gene information

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in mitochondrial inner membrane PubMed 
is_active_in mitochondrial inner membrane PubMed 
located_in mitochondrial inner membrane  
located_in mitochondrion PubMed 
located_in mitochondrion  
part_of respiratory chain complex I  
part_of respiratory chain complex I PubMed 
part_of respiratory chain complex I  
part_of respiratory chain complex I  

General protein information

Preferred Names
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
Names
NADH-ubiquinone oxidoreductase B22 subunit
complex I-B22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364808.1NP_001351737.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AW060173, BY079922, CK128431
    Conserved Domains (1) summary
    cl05087
    Location:230
    Complex1_LYR; Complex 1 protein (LYR family)
  2. NM_023172.4NP_075661.1  NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 isoform 1

    See identical proteins and their annotated locations for NP_075661.1

    Status: VALIDATED

    Source sequence(s)
    AK004522, BY079922, CK128431
    Consensus CDS
    CCDS27495.1
    UniProtKB/Swiss-Prot
    Q9CQJ8
    Related
    ENSMUSP00000022980.4, ENSMUST00000022980.5
    Conserved Domains (1) summary
    cd20263
    Location:1288
    Complex1_LYR_NDUFB9_LYRM3; LYR (leucine-tyrosine-arginine) motif found in NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 (NDUFB9) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    58805650..58811365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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