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Tomm6 translocase of outer mitochondrial membrane 6 [ Mus musculus (house mouse) ]

Gene ID: 66119, updated on 5-Mar-2024

Summary

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Official Symbol
Tomm6provided by MGI
Official Full Name
translocase of outer mitochondrial membrane 6provided by MGI
Primary source
MGI:MGI:1913369
See related
Ensembl:ENSMUSG00000033475 AllianceGenome:MGI:1913369
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110002E23Rik
Summary
Predicted to act upstream of or within protein transport. Located in mitochondrion. Is expressed in several structures, including central nervous system; genitourinary system; gut; sensory organ; and thymus. Orthologous to human TOMM6 (translocase of outer mitochondrial membrane 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 33.4), stomach adult (RPKM 30.0) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
17 C; 17 23.87 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (47997570..47999311, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (47686645..47688386, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene cyclin D3 Neighboring gene STARR-positive B cell enhancer ABC_E9169 Neighboring gene bystin-like Neighboring gene predicted gene 20517 Neighboring gene STARR-positive B cell enhancer ABC_E10959 Neighboring gene mediator complex subunit 20 Neighboring gene Kpna2 retrotransposed pseudogene Neighboring gene ubiquitin specific peptidase 49 Neighboring gene STARR-positive B cell enhancer ABC_E4218 Neighboring gene prickle planar cell polarity protein 4 Neighboring gene translocase of outer mitochondrial membrane 6, opposite strand Neighboring gene fibroblast growth factor receptor substrate 3 Neighboring gene fibroblast growth factor receptor substrate 3, opposite strand

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Chung YC, et al. Gene Expr Patterns, 2011 Jan-Feb. PMID 20932939
  2. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
  3. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
  4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  5. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
part_of mitochondrial outer membrane translocase complex IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
mitochondrial import receptor subunit TOM6 homolog
Names
overexpressed breast tumor protein homolog
translocase of outer membrane 6 kDa subunit homolog
translocase of outer mitochondrial membrane 6 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164729.1 → NP_001158201.1  mitochondrial import receptor subunit TOM6 homolog

    See identical proteins and their annotated locations for NP_001158201.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    BC089325, CA319049, CA321392
    Consensus CDS
    CCDS37643.1
    UniProtKB/Swiss-Prot
    Q9CQN3
    Related
    ENSMUSP00000108926.2, ENSMUST00000113301.2
    Conserved Domains (1) summary
    pfam15184
    Location:1 → 74
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog

  2. NM_025365.3 → NP_079641.1  mitochondrial import receptor subunit TOM6 homolog

    See identical proteins and their annotated locations for NP_079641.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK010470, BC089325, CA321392
    Consensus CDS
    CCDS37643.1
    UniProtKB/Swiss-Prot
    Q9CQN3
    Related
    ENSMUSP00000108927.4, ENSMUST00000113302.10
    Conserved Domains (1) summary
    pfam15184
    Location:1 → 74
    TOM6p; Mitochondrial import receptor subunit TOM6 homolog

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    47997570..47999311 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQN3.1 GenPept UniProtKB/Swiss-Prot:Q9CQN3

Gene LinkOut

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