U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Zfp524 zinc finger protein 524 [ Mus musculus (house mouse) ]

Gene ID: 66056, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Zfp524provided by MGI
Official Full Name
zinc finger protein 524provided by MGI
Primary source
MGI:MGI:1916740
See related
Ensembl:ENSMUSG00000051184 AllianceGenome:MGI:1916740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Znf524; 0610012F07Rik; 2300009P13Rik
Summary
Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; dorsal root ganglion; and genitourinary system. Orthologous to human ZNF524 (zinc finger protein 524). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in colon adult (RPKM 16.2), duodenum adult (RPKM 15.7) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7 A1; 7 2.9 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (5018142..5021487)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (5015216..5018493)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 53351 Neighboring gene Flt3 interacting zinc finger protein 1 Neighboring gene STARR-seq mESC enhancer starr_17950 Neighboring gene STARR-positive B cell enhancer ABC_E4889 Neighboring gene zinc finger protein 865 Neighboring gene STARR-positive B cell enhancer ABC_E3696 Neighboring gene zinc finger protein 784

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. An atlas of combinatorial transcriptional regulation in mouse and man. Ravasi T, et al. Cell, 2010 Mar 5. PMID 20211142, Free PMC Article
  2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
  3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
zinc finger protein 524

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418678.1 → NP_001405607.1  zinc finger protein 524

    Status: VALIDATED

    Source sequence(s)
    AC157563
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0
    Related
    ENSMUSP00000146921.2, ENSMUST00000207901.2

  2. NM_001418681.1 → NP_001405610.1  zinc finger protein 524

    Status: VALIDATED

    Source sequence(s)
    AC157563
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0
    Related
    ENSMUSP00000147095.2, ENSMUST00000209030.2

  3. NM_001418683.1 → NP_001405612.1  zinc finger protein 524

    Status: VALIDATED

    Source sequence(s)
    AC157563
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0

  4. NM_001418686.1 → NP_001405615.1  zinc finger protein 524

    Status: VALIDATED

    Source sequence(s)
    AC157563
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0

  5. NM_001418688.1 → NP_001405617.1  zinc finger protein 524

    Status: VALIDATED

    Source sequence(s)
    AC157563
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0

  6. NM_025324.3 → NP_079600.1  zinc finger protein 524

    See identical proteins and their annotated locations for NP_079600.1

    Status: VALIDATED

    Source sequence(s)
    AC157563
    Consensus CDS
    CCDS20752.1
    UniProtKB/Swiss-Prot
    Q9D0B1, Q9DCQ0
    Related
    ENSMUSP00000083533.4, ENSMUST00000086349.5
    Conserved Domains (2) summary
    COG5048
    Location:102 → 218
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:139 → 159
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. NR_184793.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157563

  2. NR_184794.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC157563

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    5018142..5021487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D0B1.1 GenPept UniProtKB/Swiss-Prot:Q9D0B1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous