Zfp784 zinc finger protein 784 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Zfp784provided by MGI
Official Full Name: zinc finger protein 784provided by MGI
Primary source: MGI:MGI:3606042
See related: Ensembl:ENSMUSG00000043290 AllianceGenome:MGI:3606042
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Znf784; C730049F21Rik
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within hematopoietic progenitor cell differentiation. Predicted to be active in nucleus. Orthologous to human ZNF784 (zinc finger protein 784). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in adrenal adult (RPKM 5.0), duodenum adult (RPKM 4.9) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 7 A1; 7 2.91 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (5037445..5041445, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (5034446..5038446, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables sequence-specific double-stranded DNA binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within hematopoietic progenitor cell differentiation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: zinc finger protein 784

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039532.2 → NP_001034621.1 zinc finger protein 784

See identical proteins and their annotated locations for NP_001034621.1

Status: VALIDATED

Source sequence(s)

AK050452, BB620617

Consensus CDS

CCDS20755.1

UniProtKB/Swiss-Prot

Q8BI69

UniProtKB/TrEMBL

B2RVK6

Related

ENSMUSP00000051979.5, ENSMUST00000062428.5

Conserved Domains (4) summary

COG5048
Location:193 → 297

COG5048; FOG: Zn-finger [General function prediction only]

sd00017
Location:197 → 217

ZF_C2H2; C2H2 Zn finger [structural motif]

pfam00096
Location:251 → 273

zf-C2H2; Zinc finger, C2H2 type

pfam13465
Location:209 → 234

zf-H2C2_2; Zinc-finger double domain