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TP53TG3C TP53 target 3C [ Homo sapiens (human) ]

Gene ID: 653550, updated on 3-Apr-2024

Summary

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Official Symbol
TP53TG3Cprovided by HGNC
Official Full Name
TP53 target 3Cprovided by HGNC
Primary source
HGNC:HGNC:42962
See related
Ensembl:ENSG00000205457 AllianceGenome:HGNC:42962
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TP53TG3; TP53TG3E; TP53TG3F
Summary
Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 7.4), placenta (RPKM 0.6) and 2 other tissues See more
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Genomic context

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Location:
16p11.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (33192510..33196858)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (33205547..33208179)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene COX assembly mitochondrial protein 2 homolog Neighboring gene ABHD17A pseudogene 9 Neighboring gene uncharacterized LOC124903683 Neighboring gene TP53 target 3 family member E

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Isolation and characterization of a novel TP53-inducible gene, TP53TG3. Ng CC, et al. Genes Chromosomes Cancer, 1999 Dec. PMID 10534768
  2. Identification of genes related to Parkinson's disease using expressed sequence tags. Kim JM, et al. DNA Res, 2006 Dec 31. PMID 17213182
  3. Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer. Vichas A, et al. Nat Commun, 2021 Aug 9. PMID 34373451, Free PMC Article
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC119888

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
TP53-target gene 3 protein
Names
TP53-inducible gene 3 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001205259.3 → NP_001192188.1  TP53-target gene 3 protein

    See identical proteins and their annotated locations for NP_001192188.1

    Status: VALIDATED

    Source sequence(s)
    AC138869
    Consensus CDS
    CCDS58458.1
    UniProtKB/Swiss-Prot
    B2R5K6, Q4KN31, Q9ULY9, Q9ULZ0
    Related
    ENSP00000455132.1, ENST00000561509.3

RNA

  1. NR_110914.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC138869

  2. NR_158182.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC138869

  3. NR_158183.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC138869

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    33192510..33196858
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434515.1 → XP_047290471.1  TP53-target gene 3 protein isoform X3

    Related
    ENSP00000353397.2, ENST00000360260.6

  2. XM_011545920.2 → XP_011544222.1  TP53-target gene 3 protein isoform X2

    See identical proteins and their annotated locations for XP_011544222.1

    UniProtKB/Swiss-Prot
    Q9ULZ0
    Related
    ENSP00000457790.1, ENST00000569719.5

  3. XM_017023591.2 → XP_016879080.1  TP53-target gene 3 protein isoform X1

    UniProtKB/TrEMBL
    I3L219

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001205260.1: Suppressed sequence

    Description
    NM_001205260.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ULZ0.2 GenPept UniProtKB/Swiss-Prot:Q9ULZ0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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