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Mrps14 mitochondrial ribosomal protein S14 [ Mus musculus (house mouse) ]

Gene ID: 64659, updated on 11-Apr-2024

Summary

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Official Symbol
Mrps14provided by MGI
Official Full Name
mitochondrial ribosomal protein S14provided by MGI
Primary source
MGI:MGI:1928141
See related
Ensembl:ENSMUSG00000058267 AllianceGenome:MGI:1928141
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpms14; 1810032L21Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in mitochondrial translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 38. Orthologous to human MRPS14 (mitochondrial ribosomal protein S14). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 7.1), liver E14 (RPKM 5.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 H2.1; 1 69.59 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (160022785..160028756)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (160195215..160201186)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930523C07 gene Neighboring gene RIKEN cDNA 4930562F07 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:162009351-162009552 Neighboring gene tenascin N Neighboring gene predicted gene, 53640 Neighboring gene STARR-seq mESC enhancer starr_02794 Neighboring gene STARR-seq mESC enhancer starr_02795 Neighboring gene RIKEN cDNA 4933417C20 gene Neighboring gene STARR-seq mESC enhancer starr_02796 Neighboring gene calcyclin binding protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats. Brower CS, et al. Proc Natl Acad Sci U S A, 2014 Nov 18. PMID 25369936, Free PMC Article
  2. A proteomics approach to the identification of mammalian mitochondrial small subunit ribosomal proteins. Koc EC, et al. J Biol Chem, 2000 Oct 20. PMID 10938081
  3. Ribosome. The structure of the human mitochondrial ribosome. Amunts A, et al. Science, 2015 Apr 3. PMID 25838379, Free PMC Article
  4. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  5. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
enables structural constituent of ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial translation ISO
Inferred from Sequence Orthology
more info
  
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in translation IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial small ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial small ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial small ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
part_of mitochondrial small ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in nuclear membrane ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
small ribosomal subunit protein uS14m
Names
28S ribosomal protein S14, mitochondrial
MRP-S14
S14mt
NP_001334050.1
NP_079750.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347121.1 → NP_001334050.1  small ribosomal subunit protein uS14m isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154873, BE861538
    Consensus CDS
    CCDS83613.1
    UniProtKB/TrEMBL
    D3Z2K2
    Related
    ENSMUSP00000107285.2, ENSMUST00000097193.3

  2. NM_025474.4 → NP_079750.1  small ribosomal subunit protein uS14m isoform 1

    See identical proteins and their annotated locations for NP_079750.1

    Status: VALIDATED

    Source sequence(s)
    AC154873, AK010242, AK083352
    Consensus CDS
    CCDS15405.1
    UniProtKB/Swiss-Prot
    Q3UNI7, Q9CR88
    Related
    ENSMUSP00000120075.2, ENSMUST00000135680.8
    Conserved Domains (1) summary
    pfam00253
    Location:74 → 126
    Ribosomal_S14; Ribosomal protein S14p/S29e

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    160022785..160028756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CR88.1 GenPept UniProtKB/Swiss-Prot:Q9CR88

Gene LinkOut

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