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CEP170P1 centrosomal protein 170 pseudogene 1 [ Homo sapiens (human) ]

Gene ID: 645455, updated on 10-Oct-2023

Summary

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Official Symbol
CEP170P1provided by HGNC
Official Full Name
centrosomal protein 170 pseudogene 1provided by HGNC
Primary source
HGNC:HGNC:28364
See related
AllianceGenome:HGNC:28364
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM68B; CEP170L; KIAA0470L
Summary
This locus appears to be a transcribed pseudogene similar to centrosomal protein 170kDa (CEP170). An approximately 50 kb region upstream of this locus also is homologous to CEP170, but is not transcribed. [provided by RefSeq, Jul 2008]
Expression
Biased expression in testis (RPKM 57.8), brain (RPKM 12.2) and 13 other tissues See more
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Genomic context

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Location:
4q26
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (118516325..118554204)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (121821340..121859207)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (119437480..119475359)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105379403 Neighboring gene uncharacterized LOC124900767 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:119437439-119437560 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr4:119452493-119452992 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:119454234-119454734 Neighboring gene H3K27ac hESC enhancer GRCh37_chr4:119454735-119455235 Neighboring gene ReSE screen-validated silencer GRCh37_chr4:119490834-119491031 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21847 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:119513527-119514434 Neighboring gene uncharacterized LOC729218 Neighboring gene RNA, U6 small nuclear 1054, pseudogene Neighboring gene capicua transcriptional repressor pseudogene 16

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
  2. An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders. Chen S, et al. Nat Genet, 2018 Jul. PMID 29892012, Free PMC Article
  3. Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma. Mahlokozera T, et al. Nat Commun, 2021 Nov 3. PMID 34732716, Free PMC Article
  4. An inter-species protein-protein interaction network across vast evolutionary distance. Zhong Q, et al. Mol Syst Biol, 2016 Apr 22. PMID 27107014, Free PMC Article
  5. Next-generation sequencing to generate interactome datasets. Yu H, et al. Nat Methods, 2011 Jun. PMID 21516116, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Other Names

  • centrosomal protein 170kDa pseudogene 1

Clone Names

  • KIAA0470, MGC26143

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003135.3 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC092670

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    118516325..118554204
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    121821340..121859207
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_025246.1: Suppressed sequence

    Description
    NG_025246.1: This RefSeq was permanently suppressed because it is now thought that pseudogene is transcribed.

  2. NM_153243.2: Suppressed sequence

    Description
    NM_153243.2: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q96L14.2 GenPept UniProtKB/Swiss-Prot:Q96L14

Gene LinkOut

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