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CPEB1 cytoplasmic polyadenylation element binding protein 1 [ Homo sapiens (human) ]

Gene ID: 64506, updated on 5-Mar-2024

Summary

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Official Symbol
CPEB1provided by HGNC
Official Full Name
cytoplasmic polyadenylation element binding protein 1provided by HGNC
Primary source
HGNC:HGNC:21744
See related
Ensembl:ENSG00000214575 MIM:607342; AllianceGenome:HGNC:21744
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CPEB; CPEB-1; h-CPEB; CPE-BP1; hCPEB-1
Summary
This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Expression
Biased expression in testis (RPKM 19.2), brain (RPKM 6.3) and 8 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
15q25.2
Exon count:
23
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 15 NC_000015.10 (82543201..82648795, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 15 NC_060939.1 (80407439..80513020, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 15 NC_000015.9 (83211951..83317546, complement)

Chromosome 15 - NC_000015.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6748 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6749 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr15:82825221-82825722 Neighboring gene dynamin 1 pseudogene 38 Neighboring gene ribosomal protein S17 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6750 Neighboring gene CPEB1 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 5793 Neighboring gene adaptor related protein complex 3 subunit beta 2 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6751 Neighboring gene serine and arginine rich splicing factor 9 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr15:83362511-83362661 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:83367432-83368224 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr15:83368225-83369015 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6752 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 6753 Neighboring gene epididymal protein pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease. Picó S, et al. Sci Transl Med, 2021 Sep 29. PMID 34586830
  2. Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression. Sovijit W, et al. Biochem Biophys Res Commun, 2021 Jan 1. PMID 33162033
  3. CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort. Jiao W, et al. J Ovarian Res, 2020 Apr 30. PMID 32354341, Free PMC Article
  4. Depletion of CPEB1 protects against oxidized LDL-induced endothelial apoptosis and inflammation though SIRT1/LOX-1 signalling pathway. Xu K, et al. Life Sci, 2019 Dec 15. PMID 31521690
  5. RNA-binding protein CPEB1 remodels host and viral RNA landscapes. Batra R, et al. Nat Struct Mol Biol, 2016 Dec. PMID 27775709, Free PMC Article

See all (60) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.
    Title: DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter.
  2. CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
    Title: CPEB alteration and aberrant transcriptome-polyadenylation lead to a treatable SLC19A3 deficiency in Huntington's disease.
  3. Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression.
    Title: Estrogen promotes increased breast cancer cell proliferation and migration through downregulation of CPEB1 expression.
  4. CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort.
    Title: CPEB1 deletion is not a common explanation for premature ovarian insufficiency in a Chinese cohort.
  5. CPEB1 and CPEB4 are involved in the regulation of the TAK1 and Smad signalings in human macrophages and dermal fibroblasts
    Title: CPEB1 or CPEB4 knockdown suppresses the TAK1 and Smad signalings in THP-1 macrophage-like cells and dermal fibroblasts.
  6. Study revealed that CPEB1 depletion might play an anti-inflammatory and antiapoptotic role in Ox-LDL-induced apoptosis and inflammation though SIRT1/LOX-1 signalling pathway.
    Title: Depletion of CPEB1 protects against oxidized LDL-induced endothelial apoptosis and inflammation though SIRT1/LOX-1 signalling pathway.
  7. study identifies CPEB1 as a potential regulator of disease progression of Posttraumatic Ankle Osteoarthritis
    Title: CPEB1 Expression Correlates with Severity of Posttraumatic Ankle Osteoarthritis and Aggravates Catabolic Effect of IL-1β on Chondrocytes.
  8. These findings indicated that the overexpression of miR4543p inhibited cell proliferation, migration and invasion by downregulating CPEB1.
    Title: miR‑454‑3p suppresses cell migration and invasion by targeting CPEB1 in human glioblastoma.
  9. Upon binding to p27(Kip1) 3'UTR, CPEB1 promotes elongation of poly-A tail and the subsequent translation of p27(Kip1) mRNA. This leads to higher levels of p27(Kip1) in the cell, in turn significantly inhibiting cell proliferation, and confers to CPEB1 a potential value as a tumor suppressor in Glioblastoma.
    Title: CPEB1 restrains proliferation of Glioblastoma cells through the regulation of p27(Kip1) mRNA translation.
  10. CPEB1 regulation of MMP9 mRNA expression mediates metastasis of breast cancer cells
    Title: CPEB1 mediates epithelial-to-mesenchyme transition and breast cancer metastasis.
Submit: New GeneRIF Correction See all GeneRIFs (35)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Potential readthrough

Included gene: RPS17

Homology

Clone Names

  • FLJ13203, MGC34136, MGC60106

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables mRNA 3'-UTR AU-rich region binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables mRNA 3'-UTR binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA regulatory element binding translation repressor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables mRNA regulatory element binding translation repressor activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables ribosome binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables translation factor activity, RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in cellular response to amino acid stimulus ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in cellular response to hypoxia IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to insulin stimulus IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cytoplasmic translation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of mRNA 3'-end processing IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in P-body IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in dendrite IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
part_of messenger ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in neuron projection IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
  
is_active_in synapse IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
cytoplasmic polyadenylation element-binding protein 1
Names
CPE-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079533.2 → NP_001073001.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

    See identical proteins and their annotated locations for NP_001073001.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2), also known as short, contains a distinct 5' UTR, lacks an in-frame portion of the 5' coding region, and uses an alternate in-frame splice site in the central coding region, compared to variant 1. The resulting isoform (2) has a shorter N-terminus and lacks a central 5 aa segment, compared to isoform 1. Variants 2 and 25 both encode the same isoform (2).
    Source sequence(s)
    AC010724, AF329403, AL832156
    Consensus CDS
    CCDS42072.2
    UniProtKB/Swiss-Prot
    B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
    Related
    ENSP00000483590.1, ENST00000618449.4
    Conserved Domains (4) summary
    pfam16366
    Location:429 → 484
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 341
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:352 → 435
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  2. NM_001079534.2 → NP_001073002.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001073002.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
    Source sequence(s)
    AC010724, AF329403, AK023265, AL832156, DA705313
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Related
    ENSP00000483857.1, ENST00000611163.4
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  3. NM_001079535.2 → NP_001073003.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001073003.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
    Source sequence(s)
    AC010724, AF329403, AL832156, BC035348, DA340952, DA705313
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Related
    ENSP00000477557.1, ENST00000617462.4
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  4. NM_001288819.2 → NP_001275748.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    See identical proteins and their annotated locations for NP_001275748.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Variants 3-5, 11-16, and 26-32 all encode the same isoform (3).
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Related
    ENSP00000484549.1, ENST00000620182.4
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  5. NM_001288820.2 → NP_001275749.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

    See identical proteins and their annotated locations for NP_001275749.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The encoded isoform (4) has a shorter N-terminus, compared to isoform 1. Variants 6, 34, and 35 all encode the same isoform (4).
    Source sequence(s)
    AK301728, AL832156, BM715948, BX649159, HY191346
    UniProtKB/TrEMBL
    B4DWY2
    Conserved Domains (4) summary
    pfam16366
    Location:273 → 328
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 81
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:83 → 185
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:196 → 279
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  6. NM_001365240.1 → NP_001352169.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  7. NM_001365241.1 → NP_001352170.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Related
    ENSP00000481010.1, ENST00000614918.4
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  8. NM_001365242.1 → NP_001352171.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Related
    ENSP00000507835.1, ENST00000684509.1
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  9. NM_001365243.1 → NP_001352172.1  cytoplasmic polyadenylation element-binding protein 1 isoform 6

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    UniProtKB/Swiss-Prot
    B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
    Related
    ENSP00000478598.1, ENST00000617958.4
    Conserved Domains (4) summary
    cd12723
    Location:309 → 416
    RRM1_CPEB1; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:427 → 512
    RRM2_CPEB1; RNA recognition motif 2 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    pfam16366
    Location:504 → 559
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 307
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus

  10. NM_001365244.1 → NP_001352173.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  11. NM_001365245.1 → NP_001352174.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  12. NM_001365246.1 → NP_001352175.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  13. NM_001365247.1 → NP_001352176.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  14. NM_001365248.1 → NP_001352177.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  15. NM_001365249.1 → NP_001352178.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Source sequence(s)
    AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  16. NM_001365250.1 → NP_001352179.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC245033
    Consensus CDS
    CCDS42072.2
    UniProtKB/Swiss-Prot
    B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
    Conserved Domains (4) summary
    pfam16366
    Location:429 → 484
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 341
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:352 → 435
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  17. NM_001387061.1 → NP_001373990.1  cytoplasmic polyadenylation element-binding protein 1 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18) encodes the longest isoform (7).
    Source sequence(s)
    AC105339, AC110291, AC245033
    UniProtKB/Swiss-Prot
    B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
    Conserved Domains (4) summary
    pfam16366
    Location:531 → 586
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 443
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:454 → 537
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  18. NM_001387062.1 → NP_001373991.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 7-9 and 20-24, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  19. NM_001387063.1 → NP_001373992.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 7-9, 19, and 21-24, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  20. NM_001387064.1 → NP_001373993.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 7-9, 19, 20, and 22-24, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  21. NM_001387065.1 → NP_001373994.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 7-9, 19-21, 23, and 24, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  22. NM_001387066.1 → NP_001373995.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variants 7-9, 19-22, and 24, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  23. NM_001387067.1 → NP_001373996.1  cytoplasmic polyadenylation element-binding protein 1 isoform 5

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variants 7-9 and 19-23, encodes isoform 5.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS92050.1
    UniProtKB/TrEMBL
    A0A087WXG7, A0A087X171
    Conserved Domains (4) summary
    pfam16366
    Location:526 → 581
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:31 → 334
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:336 → 438
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:449 → 532
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  24. NM_001387068.1 → NP_001373997.1  cytoplasmic polyadenylation element-binding protein 1 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variant 2, encodes isoform (2).
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS42072.2
    UniProtKB/Swiss-Prot
    B7Z6C6, Q86W46, Q8IV41, Q9BZB7, Q9BZB8, Q9H8V5
    Conserved Domains (4) summary
    pfam16366
    Location:429 → 484
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 341
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:352 → 435
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  25. NM_001387069.1 → NP_001373998.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 3-5, 11-16, and 27-32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  26. NM_001387070.1 → NP_001373999.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variants 3-5, 11-16, 26, and 28-32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  27. NM_001387071.1 → NP_001374000.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variants 3-5, 11-16, 26, 27, and 29-32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  28. NM_001387072.1 → NP_001374001.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29), as well as variants 3-5, 11-16, 26-28, and 30-32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  29. NM_001387073.1 → NP_001374002.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30), as well as variants 3-5, 11-16, 26-29, 31 and 32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  30. NM_001387074.1 → NP_001374003.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (31), as well as variants 3-5, 11-16, 26-30, and 32, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  31. NM_001387075.1 → NP_001374004.1  cytoplasmic polyadenylation element-binding protein 1 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (32), as well as variants 3-5, 11-16, and 26-31, encodes isoform 3.
    Source sequence(s)
    AC105339, AC110291, AC245033
    Consensus CDS
    CCDS45330.2
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:424 → 479
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 336
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:347 → 430
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  32. NM_001387076.1 → NP_001374005.1  cytoplasmic polyadenylation element-binding protein 1 isoform 8

    Status: REVIEWED

    Source sequence(s)
    AC105339, AC110291, AC245033
    UniProtKB/TrEMBL
    A0A0J9YXP0
    Conserved Domains (4) summary
    pfam16366
    Location:412 → 467
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 232
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:234 → 324
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:335 → 418
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  33. NM_001387077.1 → NP_001374006.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (34), as well as variants 6 and 35, encodes isoform 4.
    Source sequence(s)
    AC245033
    UniProtKB/TrEMBL
    B4DWY2
    Conserved Domains (4) summary
    pfam16366
    Location:273 → 328
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 81
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:83 → 185
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:196 → 279
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  34. NM_001387078.1 → NP_001374007.1  cytoplasmic polyadenylation element-binding protein 1 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (35), as well as variants 6 and 34, encodes isoform 4.
    Source sequence(s)
    AC245033
    UniProtKB/TrEMBL
    B4DWY2
    Conserved Domains (4) summary
    pfam16366
    Location:273 → 328
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 81
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus
    cd12723
    Location:83 → 185
    RRM1_CPEB1; RNA recognition motif 1 (RRM1) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:196 → 279
    RRM2_CPEB1; RNA recognition motif 2 (RRM2) found in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins

  35. NM_030594.5 → NP_085097.3  cytoplasmic polyadenylation element-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_085097.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AC105339, AL832156, BC050629, BM715948, BX649159, HY007452, HY191346
    Consensus CDS
    CCDS45329.2
    UniProtKB/TrEMBL
    A0A087X171
    Related
    ENSP00000477715.1, ENST00000615198.4
    Conserved Domains (4) summary
    cd12723
    Location:309 → 411
    RRM1_CPEB1; RNA recognition motif 1 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    cd12725
    Location:422 → 507
    RRM2_CPEB1; RNA recognition motif 2 in cytoplasmic polyadenylation element-binding protein 1 (CPEB-1) and similar proteins
    pfam16366
    Location:499 → 554
    CEBP_ZZ; Cytoplasmic polyadenylation element-binding protein ZZ domain
    pfam16368
    Location:1 → 307
    CEBP1_N; Cytoplasmic polyadenylation element-binding protein 1 N-terminus

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000015.10 Reference GRCh38.p14 Primary Assembly

    Range
    82543201..82648795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187606.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    332306..430793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060939.1 Alternate T2T-CHM13v2.0

    Range
    80407439..80513020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BZB8.1 GenPept UniProtKB/Swiss-Prot:Q9BZB8

Gene LinkOut

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