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LYPLAL1-DT LYPLAL1 divergent transcript [ Homo sapiens (human) ]

Gene ID: 643723, updated on 10-Oct-2023

Summary

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Official Symbol
LYPLAL1-DTprovided by HGNC
Official Full Name
LYPLAL1 divergent transcriptprovided by HGNC
Primary source
HGNC:HGNC:50560
See related
Ensembl:ENSG00000228063 AllianceGenome:HGNC:50560
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYPLAL1-AS1
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
1q41
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (219080973..219173788, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (218316969..218409758, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (219254315..219347130, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904513 Neighboring gene long intergenic non-protein coding RNA 1710 Neighboring gene MPRA-validated peak701 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1820 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2542 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2543 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2544 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2545 Neighboring gene lysophospholipase like 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 2546 Neighboring gene ribosomal modification protein rimK like family member B pseudogene 2 Neighboring gene Sharpr-MPRA regulatory region 2527 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:219572714-219573343 Neighboring gene uncharacterized LOC107984018 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 1821

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. LncRNA LYPLAL1-DT screening from type 2 diabetes with macrovascular complication contributes protective effects on human umbilical vein endothelial cells via regulating the miR-204-5p/SIRT1 axis. Zhu X, et al. Cell Death Discov, 2022 May 4. PMID 35508613, Free PMC Article
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • LYPLAL1 antisense RNA 1 (head to head)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_038845.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC092808, BC086863, DA132981
    Related
    ENST00000670257.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    219080973..219173788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    218316969..218409758 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases