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RNASE2CP ribonuclease A family member 2C, pseudogene [ Homo sapiens (human) ]

Gene ID: 643332, updated on 10-Oct-2023

Summary

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Official Symbol
RNASE2CPprovided by HGNC
Official Full Name
ribonuclease A family member 2C, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:55569
See related
AllianceGenome:HGNC:55569
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ECRP
Expression
Restricted expression toward bone marrow (RPKM 28.4) See more
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Genomic context

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Location:
14q11.2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (20919341..20920176)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (15116723..15117558)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (21387500..21388335)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370397 Neighboring gene H3K27ac hESC enhancer GRCh37_chr14:21281928-21282428 Neighboring gene ribonuclease A family member 1, pancreatic Neighboring gene Sharpr-MPRA regulatory region 8185 Neighboring gene Sharpr-MPRA regulatory region 4676 Neighboring gene MPRA-validated peak2113 silencer Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr14:21296219-21297418 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:21308316-21308816 Neighboring gene uncharacterized LOC100507513 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8096 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8097 Neighboring gene NANOG hESC enhancer GRCh37_chr14:21372529-21373030 Neighboring gene ribonuclease A family member 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:21378679-21379180 Neighboring gene RNA, 7SL, cytoplasmic 189, pseudogene Neighboring gene ribonuclease A family member 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity. Sikriwal D, et al. J Cell Biochem, 2012 Oct. PMID 22581709
  2. Faecal eosinophil cationic protein and serum immunoglobulin E in relation to infant feeding practices. Hua MC, et al. Ann Clin Biochem, 2017 Mar. PMID 27194747
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Fecal eosinophil cationic protein was not associated with total serum immunoglobulin E; immunoglobulin E might not be a useful indictor of its sensitization in infancy.
    Title: Faecal eosinophil cationic protein and serum immunoglobulin E in relation to infant feeding practices.
  2. Besides the RNase activity, loop L7 is another important determinant for the antiviral activity of eosinophil-derived neurotoxin.
    Title: An insertion in loop L7 of human eosinophil-derived neurotoxin is crucial for its antiviral activity.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • eosinophil cationic-related protein
  • ribonuclease A family member 2 pseudogene
  • ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033909.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    BC143321

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    20919341..20920176
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    15116723..15117558
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
Molecular Biology Databases