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FAM230B family with sequence similarity 230 member B [ Homo sapiens (human) ]

Gene ID: 642633, updated on 10-Oct-2023

Summary

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Official Symbol
FAM230Bprovided by HGNC
Official Full Name
family with sequence similarity 230 member Bprovided by HGNC
Primary source
HGNC:HGNC:32943
See related
Ensembl:ENSG00000215498 AllianceGenome:HGNC:32943
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Restricted expression toward testis (RPKM 11.2) See more
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Genomic context

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See FAM230B in Genome Data Viewer
Location:
22q11.21
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (21167865..21192161)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (21577645..21602006)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (21522154..21546450)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene BCR pseudogene 2 Neighboring gene POM121 transmembrane nucleoporin like 7 pseudogene Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:21483022-21483890 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:21498806-21499306 Neighboring gene E2F transcription factor 6 pseudogene 2 Neighboring gene ReSE screen-validated silencer GRCh37_chr22:21507745-21507931 Neighboring gene MPRA-validated peak4462 silencer Neighboring gene MPRA-validated peak4464 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:21555249-21555931 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:21555932-21556613 Neighboring gene family with sequence similarity 247 member A Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:21569798-21570298 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:21570299-21570799 Neighboring gene gamma-glutamyltransferase 2, pseudogene Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:21585968-21586526 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr22:21609011-21609708 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:21609709-21610404 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:21610405-21611102 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:21613263-21613765

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Long non-coding RNA FAM230B is a novel prognostic and diagnostic biomarker for lung adenocarcinoma. Cao Y, et al. Bioengineered, 2022 Mar. PMID 35287554, Free PMC Article
  2. Analysis of the subcellular location of FAM230B and its interaction with premature miR-302b in osteosarcoma. Cheng S, et al. J Bone Miner Metab, 2022 Jul. PMID 35639175
  3. The Subcellular Localization of IncRNA FAM230B in Osteosarcoma and Its Interaction with Early miR-203. Song X, et al. Crit Rev Eukaryot Gene Expr, 2022. PMID 35377981
  4. Formation of a Family of Long Intergenic Noncoding RNA Genes with an Embedded Translocation Breakpoint Motif in Human Chromosomal Low Copy Repeats of 22q11.2-Some Surprises and Questions. Delihas N. Noncoding RNA, 2018 Jul 20. PMID 30036931, Free PMC Article
  5. A family of long intergenic non-coding RNA genes in human chromosomal region 22q11.2 carry a DNA translocation breakpoint/AT-rich sequence. Delihas N. PLoS One, 2018. PMID 29668722, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Long non-coding RNA FAM230B is a novel prognostic and diagnostic biomarker for lung adenocarcinoma.
    Title: Long non-coding RNA FAM230B is a novel prognostic and diagnostic biomarker for lung adenocarcinoma.
  2. Analysis of the subcellular location of FAM230B and its interaction with premature miR-302b in osteosarcoma.
    Title: Analysis of the subcellular location of FAM230B and its interaction with premature miR-302b in osteosarcoma.
  3. The Subcellular Localization of IncRNA FAM230B in Osteosarcoma and Its Interaction with Early miR-203.
    Title: The Subcellular Localization of IncRNA FAM230B in Osteosarcoma and Its Interaction with Early miR-203.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • family with sequence similarity 230 member B (non-protein coding)

Clone Names

  • FLJ46366

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_165621.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP000550
    Related
    ENST00000451257.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    21167865..21192161
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    21577645..21602006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_201565.1: Suppressed sequence

    Description
    NM_201565.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version

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