U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SPDYE14 speedy/RINGO cell cycle regulator family member E14 [ Homo sapiens (human) ]

Gene ID: 641776, updated on 23-Nov-2023

Summary

Go to the top of the page Help
Official Symbol
SPDYE14provided by HGNC
Official Full Name
speedy/RINGO cell cycle regulator family member E14provided by HGNC
Primary source
HGNC:HGNC:51510
See related
Ensembl:ENSG00000286137 AllianceGenome:HGNC:51510
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SPDYE13; SPDYE14P
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7q11.23
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (75237205..75317429)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (76441124..76520611)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (74922383..74946599)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene general transcription factor IIi pseudogene 1 Neighboring gene uncharacterized LOC107986710 Neighboring gene PHB1 pseudogene 6 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 18293 Neighboring gene speedy/RINGO cell cycle regulator family member E13 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 13 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 10 Neighboring gene speedy/RINGO cell cycle regulator family member E15 Neighboring gene PMS1 homolog 2, mismatch repair system component pseudogene 2

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Toward a complete human genome sequence. Sanger Center, et al. Genome Res, 1998 Nov. PMID 9847074
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Phenotypes

Go to the top of the page Help

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
putative speedy protein E14
Names
Williams Beuren syndrome chromosome region 19 pseudogene
speedy homolog E1 pseudogene
speedy/RINGO cell cycle regulator family member E1 pseudogene
speedy/RINGO cell cycle regulator family member E14, pseudogene

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001382494.2 → NP_001369423.1  putative speedy protein E14

    Status: VALIDATED

    Source sequence(s)
    AC211486
    Consensus CDS
    CCDS94126.1
    UniProtKB/Swiss-Prot
    A0A494C0Z2, P0DUD3, P0DUD4
    Conserved Domains (1) summary
    pfam11357
    Location:107 → 261
    Spy1; Cell cycle regulatory protein

  2. NM_001382495.2 → NP_001369424.1  putative speedy protein E14

    Status: VALIDATED

    Source sequence(s)
    AC211486
    Consensus CDS
    CCDS94126.1
    UniProtKB/Swiss-Prot
    A0A494C0Z2, P0DUD3, P0DUD4
    Conserved Domains (1) summary
    pfam11357
    Location:107 → 261
    Spy1; Cell cycle regulatory protein

  3. NM_001394940.1 → NP_001381869.1  putative speedy protein E14

    Status: VALIDATED

    Source sequence(s)
    AC211486
    Consensus CDS
    CCDS94126.1
    UniProtKB/Swiss-Prot
    A0A494C0Z2, P0DUD3, P0DUD4
    Related
    ENSP00000498497.1, ENST00000651045.3
    Conserved Domains (1) summary
    pfam11357
    Location:107 → 261
    Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    75237205..75317429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047420696.1 → XP_047276652.1  putative speedy protein E14 isoform X1

    UniProtKB/Swiss-Prot
    A0A494C0Z2, P0DUD3, P0DUD4

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    76441124..76520611
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_041823.1: Suppressed sequence

    Description
    NG_041823.1: This RefSeq was removed because it is now thought that this locus is transcribed.

  2. NR_146072.1: Suppressed sequence

    Description
    NR_146072.1: This RefSeq was removed because it is now thought that this gene does encode a protein.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0DUD3.1 GenPept UniProtKB/Swiss-Prot:P0DUD3

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials