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Spint5 serine protease inhibitor, Kunitz type 5 [ Mus musculus (house mouse) ]

Gene ID: 641368, updated on 8-Feb-2024

Summary

Official Symbol
Spint5provided by MGI
Official Full Name
serine protease inhibitor, Kunitz type 5provided by MGI
Primary source
MGI:MGI:3651687
See related
Ensembl:ENSMUSG00000074593 AllianceGenome:MGI:3651687
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm14316
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Orthologous to human SPINT5P (serine peptidase inhibitor, Kunitz type 5, pseudogene). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 61.3) See more
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Genomic context

Location:
2 H3; 2 85.27 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164557225..164559988)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164715305..164718068)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 13 Neighboring gene serine protease inhibitor, Kunitz type 4 Neighboring gene WAP four-disulfide core domain 3 Neighboring gene deoxynucleotidyltransferase, terminal, interacting protein 1 Neighboring gene STARR-seq mESC enhancer starr_06333

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General protein information

Preferred Names
serine protease inhibitor, Kunitz type 5
Names
KUNITZ5
Spint5 (KUNITZ5)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040055.1NP_001035144.1  serine protease inhibitor, Kunitz type 5 precursor

    See identical proteins and their annotated locations for NP_001035144.1

    Status: PROVISIONAL

    Source sequence(s)
    AY542490
    Consensus CDS
    CCDS17052.1
    UniProtKB/TrEMBL
    J3KMK8, Q32ZM2
    Related
    ENSMUSP00000099386.4, ENSMUST00000103097.10
    Conserved Domains (1) summary
    smart00131
    Location:4899
    KU; BPTI/Kunitz family of serine protease inhibitors

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    164557225..164559988
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)