U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Wfdc9 WAP four-disulfide core domain 9 [ Mus musculus (house mouse) ]

Gene ID: 629754, updated on 5-Mar-2024

Summary

Official Symbol
Wfdc9provided by MGI
Official Full Name
WAP four-disulfide core domain 9provided by MGI
Primary source
MGI:MGI:3652032
See related
Ensembl:ENSMUSG00000074594 AllianceGenome:MGI:3652032
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in antibacterial humoral response and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Orthologous to human WFDC9 (WAP four-disulfide core domain 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 180.3) See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Wfdc9 in Genome Data Viewer
Location:
2 H3; 2 85.24 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (164491547..164499263, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (164649625..164657343, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene WAP four-disulfide core domain 16 Neighboring gene ribosomal protein S27 pseudogene Neighboring gene WAP four-disulfide core domain 10 Neighboring gene WAP four-disulfide core domain 11 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:164504826-164505027 Neighboring gene WAP four-disulfide core domain 13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in antibacterial humoral response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001160414.2NP_001153886.1  protein WFDC9 precursor

    See identical proteins and their annotated locations for NP_001153886.1

    Status: VALIDATED

    Source sequence(s)
    AL591478
    Consensus CDS
    CCDS50796.1
    UniProtKB/Swiss-Prot
    Q3UW41
    Related
    ENSMUSP00000104959.2, ENSMUST00000109335.8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    164491547..164499263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499984.4XP_006500047.3  protein WFDC9 isoform X1