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Vmn2r8 vomeronasal 2, receptor 8 [ Mus musculus (house mouse) ]

Gene ID: 627479, updated on 11-Apr-2024

Summary

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Official Symbol
Vmn2r8provided by MGI
Official Full Name
vomeronasal 2, receptor 8provided by MGI
Primary source
MGI:MGI:3642986
See related
Ensembl:ENSMUSG00000090961 AllianceGenome:MGI:3642986
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG627479
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
5 F; 5 53.24 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (108945059..108956620, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (108797193..108808754, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 212 Neighboring gene RIKEN cDNA 1700047L14 gene Neighboring gene transmembrane p24 trafficking protein 11 Neighboring gene coiled-coil domain containing 77 pseudogene Neighboring gene vomeronasal 2, receptor 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal 2, receptor 8
Names
vomeronasal receptor Vmn2r8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104620.1 → NP_001098090.1  vomeronasal 2, receptor 8 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AC123743, AC140291
    Consensus CDS
    CCDS51594.1
    UniProtKB/TrEMBL
    A0A3B2WCB9, L7N472
    Related
    ENSMUSP00000126953.2, ENSMUST00000172140.3
    Conserved Domains (3) summary
    cd06365
    Location:40 → 499
    PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam00003
    Location:595 → 829
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam07562
    Location:508 → 560
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    108945059..108956620 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165404.1 → XP_036021297.1  vomeronasal 2, receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A3B2WCB9
    Conserved Domains (3) summary
    cd15283
    Location:580 → 831
    7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
    cd06365
    Location:45 → 499
    PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam07562
    Location:507 → 560
    NCD3G; Nine Cysteines Domain of family 3 GPCR

  2. XM_017321057.1 → XP_017176546.1  vomeronasal 2, receptor 8 isoform X2

    Conserved Domains (1) summary
    cl10011
    Location:45 → 430
    Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
Nucleotide Protein
Heading Accession and Version

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