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Vmn2r90 vomeronasal 2, receptor 90 [ Mus musculus (house mouse) ]

Gene ID: 626942, updated on 11-Apr-2024

Summary

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Official Symbol
Vmn2r90provided by MGI
Official Full Name
vomeronasal 2, receptor 90provided by MGI
Primary source
MGI:MGI:3645076
See related
Ensembl:ENSMUSG00000092120 AllianceGenome:MGI:3645076
Gene type
protein coding
RefSeq status
INFERRED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG626942
Summary
Predicted to enable G protein-coupled receptor activity. Predicted to be integral component of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
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Genomic context

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Location:
17 A3.2; 17 10.14 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (17924203..17954429)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (17703941..17734167)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene leucyl/cystinyl aminopeptidase Neighboring gene STARR-positive B cell enhancer ABC_E5575 Neighboring gene STARR-positive B cell enhancer ABC_E7491 Neighboring gene STARR-seq mESC enhancer starr_41962 Neighboring gene STARR-positive B cell enhancer ABC_E4194 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:17762259-17762524 Neighboring gene STARR-positive B cell enhancer ABC_E7492 Neighboring gene farnesyl diphosphate synthetase pseudogene Neighboring gene STARR-seq mESC enhancer starr_41964 Neighboring gene STARR-seq mESC enhancer starr_41965 Neighboring gene STARR-seq mESC enhancer starr_41966 Neighboring gene microRNA let7e Neighboring gene sperm acrosome associated 6 Neighboring gene microRNA 99b

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. V2R gene families degenerated in primates, dog and cow, but expanded in opossum. Young JM, et al. Trends Genet, 2007 May. PMID 17382427
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables G protein-coupled receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
vomeronasal receptor Vmn2r90

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104539.1 → NP_001098009.1  vomeronasal receptor Vmn2r90 precursor

    Status: INFERRED

    Source sequence(s)
    AC121822
    Consensus CDS
    CCDS49966.1
    UniProtKB/TrEMBL
    E9PXJ8
    Related
    ENSMUSP00000126650.2, ENSMUST00000169805.3
    Conserved Domains (4) summary
    cd06365
    Location:36 → 506
    PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
    pfam00003
    Location:601 → 835
    7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
    pfam01094
    Location:77 → 470
    ANF_receptor; Receptor family ligand binding region
    pfam07562
    Location:515 → 566
    NCD3G; Nine Cysteines Domain of family 3 GPCR

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    17924203..17954429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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