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Zfp951 zinc finger protein 951 [ Mus musculus (house mouse) ]

Gene ID: 626391, updated on 8-Feb-2024

Summary

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Official Symbol
Zfp951provided by MGI
Official Full Name
zinc finger protein 951provided by MGI
Primary source
MGI:MGI:2441896
See related
Ensembl:ENSMUSG00000072774 AllianceGenome:MGI:2441896
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm38611; C230055K05Rik
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZNF101 (zinc finger protein 101). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 1.6), thymus adult (RPKM 1.1) and 26 other tissues See more
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Genomic context

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See Zfp951 in Genome Data Viewer
Location:
5 E5; 5 50.68 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (104950112..105007988, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (104802246..104860157, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene taxilin gamma pseudogene Neighboring gene STARR-seq mESC enhancer starr_13838 Neighboring gene STARR-seq mESC enhancer starr_13839 Neighboring gene STARR-seq mESC enhancer starr_13840 Neighboring gene STARR-seq mESC enhancer starr_13841 Neighboring gene STARR-seq mESC enhancer starr_13842 Neighboring gene STARR-seq mESC enhancer starr_13843 Neighboring gene NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 pseudogene Neighboring gene predicted gene, 29714

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
kruppel-related zinc finger protein-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001039231.3 → NP_001034320.3  kruppel-related zinc finger protein-like

    Status: VALIDATED

    Source sequence(s)
    AC110537, AK132470, BY735223, CD807221
    Consensus CDS
    CCDS80351.1
    UniProtKB/TrEMBL
    A0A087WRH0
    Related
    ENSMUSP00000140625.2, ENSMUST00000186219.7
    Conserved Domains (5) summary
    smart00349
    Location:28 → 69
    KRAB; krueppel associated box
    COG5048
    Location:286 → 439
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:290 → 310
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:28 → 64
    KRAB; KRAB box
    pfam13465
    Location:358 → 382
    zf-H2C2_2; Zinc-finger double domain

RNA

  1. NR_155269.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC110537

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    104950112..105007988 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165401.1 → XP_036021294.1  kruppel-related zinc finger protein-like isoform X1

    Conserved Domains (3) summary
    COG5048
    Location:300 → 453
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:304 → 324
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:42 → 82
    KRAB; KRAB box

  2. XM_036165402.1 → XP_036021295.1  kruppel-related zinc finger protein-like isoform X3

    Conserved Domains (3) summary
    COG5048
    Location:271 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:275 → 295
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 53
    KRAB; KRAB box

  3. XM_030254749.2 → XP_030110609.1  kruppel-related zinc finger protein-like isoform X2

    Conserved Domains (3) summary
    COG5048
    Location:271 → 424
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:275 → 295
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam01352
    Location:13 → 53
    KRAB; KRAB box

  4. XM_036165403.1 → XP_036021296.1  kruppel-related zinc finger protein-like isoform X4

    Conserved Domains (2) summary
    COG5048
    Location:230 → 383
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:234 → 254
    ZF_C2H2; C2H2 Zn finger [structural motif]

RNA

  1. XR_004942546.1 RNA Sequence

  2. XR_003955690.2 RNA Sequence

  3. XR_001784732.3 RNA Sequence

  4. XR_003955688.2 RNA Sequence

  5. XR_003955689.1 RNA Sequence

  6. XR_003955687.1 RNA Sequence

  7. XR_004942547.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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