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Trbv1 T cell receptor beta, variable 1 [ Mus musculus (house mouse) ]

Gene ID: 621968, updated on 8-Feb-2024

Summary

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Official Symbol
Trbv1provided by MGI
Official Full Name
T cell receptor beta, variable 1provided by MGI
Primary source
MGI:MGI:98594
See related
Ensembl:ENSMUSG00000076461 IMGT/GENE-DB:TRBV1; AllianceGenome:MGI:98594
Gene type
other
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm6273; Tcrb-V2; TCRBV2S1
Summary
Enables peptide antigen binding activity. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See Trbv1 in Genome Data Viewer
Location:
6 18.93 cM; 6 B1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (40868230..40868819)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (40891296..40891885)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene maltase-glucoamylase 2, pseudogene Neighboring gene STARR-seq mESC enhancer starr_15690 Neighboring gene monooxygenase, DBH-like 2 Neighboring gene serine protease 58 Neighboring gene T cell receptor beta chain Neighboring gene serine protease 59

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Receptor diversity of insulin-specific T cell lines from C57BL (H-2b) mice. Spinella DG, et al. J Immunol, 1987 Jun 1. PMID 2953795
  2. Vβ2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen. Patel O, et al. Proc Natl Acad Sci U S A, 2011 Nov 22. PMID 22065767, Free PMC Article
  3. The murine T-cell receptor uses a limited repertoire of expressed V beta gene segments. Barth RK, et al. Nature, 1985 Aug 8-14. PMID 2412120
  4. Polymorphism of Tcrb and Tcrg genes in Biozzi mice: segregation analysis of a new Tcrg haplotype with antibody responsiveness. Vidard L, et al. Immunogenetics, 1990. PMID 1973682
  5. A T cell clone expresses two T cell receptor alpha genes but uses one alpha beta heterodimer for allorecognition and self MHC-restricted antigen recognition. Malissen M, et al. Cell, 1988 Oct 7. PMID 3262424

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Other Names

  • T-cell receptor beta, variable 2
  • TCR V beta chain

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables peptide antigen binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peptide antigen binding IDA
Inferred from Direct Assay
more info
 PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_006980.1 

    Range
    502..1091
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    40868230..40868819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases