U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Lcn6 lipocalin 6 [ Mus musculus (house mouse) ]

Gene ID: 620709, updated on 9-May-2024

Summary

Go to the top of the page Help
Official Symbol
Lcn6provided by MGI
Official Full Name
lipocalin 6provided by MGI
Primary source
MGI:MGI:3045364
See related
Ensembl:ENSMUSG00000045684 AllianceGenome:MGI:3045364
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9230101D24Rik
Summary
Orthologous to human LCN6 (lipocalin 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Restricted expression toward genital fat pad adult (RPKM 67.7) See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
2 A3; 2 17.73 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25566650..25571620)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25676638..25681608)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene lipocalin 8 Neighboring gene lipocalin 5 Neighboring gene lipocalin 10 Neighboring gene odorant binding protein 2A

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Impaired sperm maturation in conditional Lcn6 knockout mice. Yin Q, et al. Biol Reprod, 2018 Jan 1. PMID 29045572
  2. Update on the human and mouse lipocalin (LCN) gene family, including evidence the mouse Mup cluster is result of an "evolutionary bloom". Charkoftaki G, et al. Hum Genomics, 2019 Feb 19. PMID 30782214, Free PMC Article
  3. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • 9230101D24Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

Go to the top of the page Help
Preferred Names
epididymal-specific lipocalin-6

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276448.1 → NP_001263377.1  epididymal-specific lipocalin-6 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001263377.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BB584268, FJ465143, FJ465144
    UniProtKB/TrEMBL
    G8XSM1
    Conserved Domains (1) summary
    pfam00061
    Location:33 → 161
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

  2. NM_177840.4 → NP_808508.2  epididymal-specific lipocalin-6 isoform 2 precursor

    See identical proteins and their annotated locations for NP_808508.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    BB584268, FJ465143
    Consensus CDS
    CCDS50535.1
    UniProtKB/TrEMBL
    A2AJB9
    Related
    ENSMUSP00000109837.2, ENSMUST00000114199.8
    Conserved Domains (1) summary
    pfam00061
    Location:33 → 161
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    25566650..25571620
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006498215.4 → XP_006498278.1  epididymal-specific lipocalin-6 isoform X5

    Conserved Domains (1) summary
    cl10502
    Location:21 → 79
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

  2. XM_006498211.4 → XP_006498274.1  epididymal-specific lipocalin-6 isoform X1

    Conserved Domains (1) summary
    cl10502
    Location:21 → 171
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

  3. XM_006498212.4 → XP_006498275.1  epididymal-specific lipocalin-6 isoform X2

    Conserved Domains (1) summary
    cl10502
    Location:21 → 171
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

  4. XM_006498213.4 → XP_006498276.1  epididymal-specific lipocalin-6 isoform X3

    Conserved Domains (1) summary
    cl10502
    Location:21 → 164
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family

  5. XM_006498214.4 → XP_006498277.1  epididymal-specific lipocalin-6 isoform X4

    Conserved Domains (1) summary
    cl10502
    Location:21 → 171
    lipocalin_FABP; lipocalin/cytosolic fatty acid-binding protein family
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous