Ugt1a8 UDP glucuronosyltransferase 1 family, polypeptide A8 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ugt1a8provided by MGI
Official Full Name: UDP glucuronosyltransferase 1 family, polypeptide A8provided by MGI
Primary source: MGI:MGI:3576090
See related: Ensembl:ENSMUSG00000089675 AllianceGenome:MGI:3576090
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: A116
Summary: Predicted to enable glucuronosyltransferase activity. Predicted to be involved in flavonoid glucuronidation and xenobiotic glucuronidation. [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 1 D; 1 44.5 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (88015550..88146720)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (88087828..88218998)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables enzyme binding	IBA Inferred from Biological aspect of Ancestor more info
enables enzyme binding	ISO Inferred from Sequence Orthology more info
enables enzyme inhibitor activity	ISO Inferred from Sequence Orthology more info
enables fatty acid binding	ISO Inferred from Sequence Orthology more info
enables glucuronosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables protein heterodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info
enables protein kinase C binding	ISO Inferred from Sequence Orthology more info
enables steroid binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cellular glucuronidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in coumarin catabolic process	ISO Inferred from Sequence Orthology more info
involved_in liver development	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: UDP-glucuronosyltransferase 1A8-like

Names: UDP-glucuronosyltransferase 1-8 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001378375.1 → NP_001365304.1 UDP-glucuronosyltransferase 1A8-like precursor

Status: VALIDATED

Source sequence(s)

AC087780, AC087801

UniProtKB/TrEMBL

D3Z748

Related

ENSMUSP00000108764.2, ENSMUST00000113139.2

Conserved Domains (1) summary

pfam00201
Location:26 → 521

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase