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Mrpl38 mitochondrial ribosomal protein L38 [ Mus musculus (house mouse) ]

Gene ID: 60441, updated on 5-Mar-2024

Summary

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Official Symbol
Mrpl38provided by MGI
Official Full Name
mitochondrial ribosomal protein L38provided by MGI
Primary source
MGI:MGI:1926269
See related
Ensembl:ENSMUSG00000020775 AllianceGenome:MGI:1926269
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpml3; MRP-L3; 1110036N21Rik; 4733401F03Rik
Summary
Located in mitochondrion. Is expressed in several structures, including brain ventricular layer; early conceptus; gonad; thymus primordium; and vibrissa. Orthologous to human MRPL38 (mitochondrial ribosomal protein L38). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 49.6), duodenum adult (RPKM 29.7) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 E2; 11 80.91 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (116022643..116029694, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (116131817..116138868, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene tripartite motif-containing 47 Neighboring gene tripartite motif-containing 65 Neighboring gene STARR-positive B cell enhancer ABC_E4017 Neighboring gene STARR-seq mESC enhancer starr_31194 Neighboring gene Fas binding factor 1 Neighboring gene predicted gene, 26413 Neighboring gene acyl-Coenzyme A oxidase 1, palmitoyl Neighboring gene STARR-seq mESC enhancer starr_31195

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle. Graack HR, et al. Biochemistry, 1999 Dec 14. PMID 10600119
  2. Expression analysis of mammalian mitochondrial ribosomal protein genes. Cheong A, et al. Gene Expr Patterns, 2020 Dec. PMID 32987154, Free PMC Article
  3. Structure of the large ribosomal subunit from human mitochondria. Brown A, et al. Science, 2014 Nov 7. PMID 25278503, Free PMC Article
  4. Structure and Function of the Mitochondrial Ribosome. Greber BJ, et al. Annu Rev Biochem, 2016 Jun 2. PMID 27023846
  5. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC8310, MGC41062

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
 PubMed 
part_of mitochondrial large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
 PubMed 
located_in mitochondrial ribosome ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  
located_in ribosome IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
large ribosomal subunit protein mL38
Names
39S ribosomal protein L38, mitochondrial
L38mt
MRP-L38
ribosomal protein, mitochondrial, L3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024177.3 → NP_077139.2  large ribosomal subunit protein mL38 precursor

    See identical proteins and their annotated locations for NP_077139.2

    Status: VALIDATED

    Source sequence(s)
    AK151598, AK159033, AV094474, BC030739
    Consensus CDS
    CCDS25658.2
    UniProtKB/Swiss-Prot
    A2A869, Q3TXY6, Q8BTZ1, Q8K2M0, Q99LM1
    Related
    ENSMUSP00000102047.2, ENSMUST00000106439.2
    Conserved Domains (1) summary
    cd00866
    Location:171 → 321
    PEBP_euk; PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in eukaryotes

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    116022643..116029694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8K2M0.2 GenPept UniProtKB/Swiss-Prot:Q8K2M0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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