Chst7 carbohydrate sulfotransferase 7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Chst7provided by MGI
Official Full Name: carbohydrate sulfotransferase 7provided by MGI
Primary source: MGI:MGI:1891767
See related: Ensembl:ENSMUSG00000037347 AllianceGenome:MGI:1891767
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: GST5; C6ST-2; Gn6st-4; glcNAc6ST-4; 2600013M07Rik
Summary: Predicted to enable N-acetylglucosamine 6-O-sulfotransferase activity and chondroitin 6-sulfotransferase activity. Predicted to be involved in N-acetylglucosamine metabolic process and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; heart; liver; lung; and tail unsegmented mesenchyme. Orthologous to human CHST7 (carbohydrate sulfotransferase 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in lung adult (RPKM 3.9), ovary adult (RPKM 3.0) and 27 other tissues See more
Orthologs: human all
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Genomic context

Location:: X A1.3; X 15.5 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (19925202..19965361)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (20058963..20099991)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Markers

Chst7 (e-PCR), detects polymorphism
- UniSTS:516438

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables N-acetylglucosamine 6-O-sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables N-acetylglucosamine 6-O-sulfotransferase activity	ISO Inferred from Sequence Orthology more info
enables chondroitin 6-sulfotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables chondroitin 6-sulfotransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables chondroitin 6-sulfotransferase activity	ISO Inferred from Sequence Orthology more info	PubMed
enables sulfotransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in N-acetylglucosamine metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in N-acetylglucosamine metabolic process	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in chondroitin sulfate biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in chondroitin sulfate biosynthetic process	ISO Inferred from Sequence Orthology more info	PubMed
involved_in sulfur compound metabolic process	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IDA Inferred from Direct Assay more info	PubMed
located_in Golgi membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in trans-Golgi network	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: carbohydrate sulfotransferase 7

Names: N-acetylglucosamine 6-O-sulfotransferase 1; N-acetylglucosamine 6-O-sulfotransferase 4; carbohydrate (N-acetylglucosamino) sulfotransferase 7; chondroitin 6-sulfotransferase 2; galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5

NP_068361.1

EC 2.8.2.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.