U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tceal3 transcription elongation factor A (SII)-like 3 [ Mus musculus (house mouse) ]

Gene ID: 594844, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Tceal3provided by MGI
Official Full Name
transcription elongation factor A (SII)-like 3provided by MGI
Primary source
MGI:MGI:1913354
See related
Ensembl:ENSMUSG00000044550 AllianceGenome:MGI:1913354
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1100001D19Rik
Summary
Predicted to enable WW domain binding activity. Predicted to be active in nucleus. Is expressed in several structures, including diaphragm; limb segment; nervous system; retina layer; and skeletal musculature. Orthologous to human TCEAL3 (transcription elongation factor A like 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 55.6), cortex adult (RPKM 42.2) and 8 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
X F1; X 59.1 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (135491586..135569127)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (136590837..136668378)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene presenilin associated, rhomboid-like pseudogene Neighboring gene nuclear encoded tRNA alanine 1 (anticodon TGC) Neighboring gene acyl-protein thioesterase 1 pseudogene Neighboring gene predicted gene, 39536 Neighboring gene transcription elongation factor A (SII)-like 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Developmentally upregulated transcriptional elongation factor a like 3 suppresses axon regeneration after optic nerve injury. Lukomska A, et al. Neurosci Lett, 2021 Nov 20. PMID 34560191, Free PMC Article
  2. Characterization of an eutherian gene cluster generated after transposon domestication identifies Bex3 as relevant for advanced neurological functions. Navas-Pérez E, et al. Genome Biol, 2020 Oct 26. PMID 33100228, Free PMC Article
  3. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Developmentally upregulated transcriptional elongation factor a like 3 suppresses axon regeneration after optic nerve injury.
    Title: Developmentally upregulated transcriptional elongation factor a like 3 suppresses axon regeneration after optic nerve injury.
Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
transcription elongation factor A protein-like 3
Names
TCEA-like protein 3
transcription elongation factor S-II protein-like 3

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001029978.3 → NP_001025149.2  transcription elongation factor A protein-like 3

    See identical proteins and their annotated locations for NP_001025149.2

    Status: VALIDATED

    Source sequence(s)
    AK017585, BY124512, CB522987
    Consensus CDS
    CCDS30420.1
    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Related
    ENSMUSP00000059401.5, ENSMUST00000060904.11
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  2. NM_001359277.1 → NP_001346206.1  transcription elongation factor A protein-like 3

    Status: VALIDATED

    Source sequence(s)
    AK158996, BY124512, CB522987
    Consensus CDS
    CCDS30420.1
    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Related
    ENSMUSP00000108724.2, ENSMUST00000113100.2
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  3. NM_001359278.1 → NP_001346207.1  transcription elongation factor A protein-like 3

    Status: VALIDATED

    Source sequence(s)
    AL671887, CB522987
    Consensus CDS
    CCDS30420.1
    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Related
    ENSMUSP00000117087.2, ENSMUST00000128040.2
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  4. NM_001359279.1 → NP_001346208.1  transcription elongation factor A protein-like 3

    Status: VALIDATED

    Source sequence(s)
    AL671887, BY262982, CB522987
    Consensus CDS
    CCDS30420.1
    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    135491586..135569127
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006528586.4 → XP_006528649.1  transcription elongation factor A protein-like 3 isoform X1

    See identical proteins and their annotated locations for XP_006528649.1

    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  2. XM_030251459.2 → XP_030107319.1  transcription elongation factor A protein-like 3 isoform X1

    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  3. XM_030251460.1 → XP_030107320.1  transcription elongation factor A protein-like 3 isoform X1

    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family

  4. XM_030251461.1 → XP_030107321.1  transcription elongation factor A protein-like 3 isoform X1

    UniProtKB/Swiss-Prot
    A2AEC3, Q8R0A5, Q9CYK5, Q9D1S4
    Conserved Domains (1) summary
    pfam04538
    Location:80 → 170
    BEX; Brain expressed X-linked like family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R0A5.2 GenPept UniProtKB/Swiss-Prot:Q8R0A5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous