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Pcbp3 poly(rC) binding protein 3 [ Mus musculus (house mouse) ]

Gene ID: 59093, updated on 11-Apr-2024

Summary

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Official Symbol
Pcbp3provided by MGI
Official Full Name
poly(rC) binding protein 3provided by MGI
Primary source
MGI:MGI:1890470
See related
Ensembl:ENSMUSG00000001120 AllianceGenome:MGI:1890470
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AlphaCP-3
Summary
Enables C-rich single-stranded DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and double-stranded DNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PCBP3 (poly(rC) binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 58.9), frontal lobe adult (RPKM 37.3) and 13 other tissues See more
Orthologs
human all
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Genomic context

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See Pcbp3 in Genome Data Viewer
Location:
10 C1; 10 39.72 cM
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (76597688..76797951, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (76761854..76962117, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35608 Neighboring gene collagen, type VI, alpha 1 Neighboring gene STARR-seq mESC enhancer starr_27183 Neighboring gene STARR-seq mESC enhancer starr_27185 Neighboring gene STARR-seq mESC enhancer starr_27186 Neighboring gene STARR-positive B cell enhancer mm9_chr10:76424592-76424893 Neighboring gene predicted gene, 35664 Neighboring gene predicted gene, 35721 Neighboring gene STARR-seq mESC enhancer starr_27188

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene. Choi HS, et al. FASEB J, 2007 Dec. PMID 17625070
  2. Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence. Kang DH, et al. Gene, 2012 Jun 10. PMID 22521865
  3. Genomic organization of the mouse Msh4 gene producing bicistronic, chimeric and antisense mRNA. Hirano M, et al. Gene, 2004 Nov 10. PMID 15527976
  4. Identification of two novel mammalian genes establishes a subfamily of KH-domain RNA-binding proteins. Makeyev AV, et al. Genomics, 2000 Aug 1. PMID 10936052
  5. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, et al. Nature, 2002 Dec 5. PMID 12466855

See all (34) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. This study demonstrates for the first time that PCBP3 can function as a repressor dependent on binding to single-strand and double-stranded poly(C) sequences.
    Title: Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence.
  2. Represses mu opioid receptor gene promoter at the transcriptional level.
    Title: Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables C-rich single-stranded DNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
poly(rC)-binding protein 3
Names
alpha-CP3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347216.1 → NP_001334145.1  poly(rC)-binding protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AK034811, AK079564, BY275026, CF730556
    Consensus CDS
    CCDS83716.1
    UniProtKB/Swiss-Prot
    P57722
    Conserved Domains (2) summary
    cd00105
    Location:294 → 356
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  2. NM_021568.2 → NP_067543.2  poly(rC)-binding protein 3 isoform 1

    See identical proteins and their annotated locations for NP_067543.2

    Status: VALIDATED

    Source sequence(s)
    AK079564, BB267036, BY275026, BY277145
    Consensus CDS
    CCDS35946.2
    UniProtKB/Swiss-Prot
    P57722, Q8BSB0, Q8C544
    Related
    ENSMUSP00000001148.5, ENSMUST00000001148.11
    Conserved Domains (3) summary
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:286 → 360
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:38 → 114
    KH-I; K homology (KH) RNA-binding domain, type I

RNA

  1. NR_152849.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC168275, BC042440, CF730556
    Related
    ENSMUST00000168505.8

  2. NR_152850.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC168276, BC042440, BE981272, CF730556

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    76597688..76797951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513926.4 → XP_006513989.1  poly(rC)-binding protein 3 isoform X10

    Conserved Domains (2) summary
    cd00105
    Location:274 → 336
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  2. XM_006513925.4 → XP_006513988.1  poly(rC)-binding protein 3 isoform X9

    Conserved Domains (2) summary
    cd00105
    Location:275 → 337
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  3. XM_006513922.4 → XP_006513985.1  poly(rC)-binding protein 3 isoform X4

    Conserved Domains (2) summary
    cd00105
    Location:297 → 359
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  4. XM_006513920.4 → XP_006513983.1  poly(rC)-binding protein 3 isoform X2

    Conserved Domains (4) summary
    pfam03154
    Location:181 → 314
    Atrophin-1; Atrophin-1 family
    cd22516
    Location:38 → 114
    KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:308 → 382
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

  5. XM_006513921.4 → XP_006513984.1  poly(rC)-binding protein 3 isoform X3

    Conserved Domains (2) summary
    cd00105
    Location:298 → 360
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  6. XM_006513916.4 → XP_006513979.1  poly(rC)-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006513979.1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  7. XM_030245199.1 → XP_030101059.1  poly(rC)-binding protein 3 isoform X12

    Conserved Domains (3) summary
    cd22519
    Location:93 → 171
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:233 → 307
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:6 → 82
    KH-I; K homology (KH) RNA-binding domain, type I

  8. XM_030245196.2 → XP_030101056.1  poly(rC)-binding protein 3 isoform X8

    Conserved Domains (4) summary
    pfam03154
    Location:149 → 282
    Atrophin-1; Atrophin-1 family
    cd22516
    Location:6 → 82
    KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22519
    Location:93 → 171
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:276 → 350
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

  9. XM_011243517.4 → XP_011241819.1  poly(rC)-binding protein 3 isoform X7

    See identical proteins and their annotated locations for XP_011241819.1

    Conserved Domains (4) summary
    pfam03154
    Location:149 → 283
    Atrophin-1; Atrophin-1 family
    cd22516
    Location:6 → 82
    KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22519
    Location:93 → 171
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:277 → 351
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

  10. XM_036155904.1 → XP_036011797.1  poly(rC)-binding protein 3 isoform X2

    Conserved Domains (4) summary
    pfam03154
    Location:181 → 314
    Atrophin-1; Atrophin-1 family
    cd22516
    Location:38 → 114
    KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:308 → 382
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

  11. XM_006513919.5 → XP_006513982.1  poly(rC)-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006513982.1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  12. XM_011243516.4 → XP_011241818.1  poly(rC)-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_011241818.1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  13. XM_030245192.2 → XP_030101052.1  poly(rC)-binding protein 3 isoform X2

    Conserved Domains (4) summary
    pfam03154
    Location:181 → 314
    Atrophin-1; Atrophin-1 family
    cd22516
    Location:38 → 114
    KH-I_PCBP3_rpt1; first type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:308 → 382
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins

  14. XM_030245190.2 → XP_030101050.1  poly(rC)-binding protein 3 isoform X1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  15. XM_030245198.2 → XP_030101058.1  poly(rC)-binding protein 3 isoform X11

    Conserved Domains (3) summary
    cd22519
    Location:93 → 171
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:254 → 328
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:6 → 82
    KH-I; K homology (KH) RNA-binding domain, type I

  16. XM_030245195.2 → XP_030101055.1  poly(rC)-binding protein 3 isoform X6

    Related
    ENSMUSP00000101051.3, ENSMUST00000105411.9
    Conserved Domains (2) summary
    cd00105
    Location:294 → 356
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  17. XM_030245197.2 → XP_030101057.1  poly(rC)-binding protein 3 isoform X9

    Conserved Domains (2) summary
    cd00105
    Location:275 → 337
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  18. XM_036155906.1 → XP_036011799.1  poly(rC)-binding protein 3 isoform X5

    UniProtKB/Swiss-Prot
    P57722, Q8BSB0, Q8C544
    Conserved Domains (3) summary
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:286 → 360
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:38 → 114
    KH-I; K homology (KH) RNA-binding domain, type I

  19. XM_030245193.2 → XP_030101053.1  poly(rC)-binding protein 3 isoform X5

    UniProtKB/Swiss-Prot
    P57722, Q8BSB0, Q8C544
    Conserved Domains (3) summary
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:286 → 360
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:38 → 114
    KH-I; K homology (KH) RNA-binding domain, type I

  20. XM_036155905.1 → XP_036011798.1  poly(rC)-binding protein 3 isoform X5

    UniProtKB/Swiss-Prot
    P57722, Q8BSB0, Q8C544
    Conserved Domains (3) summary
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:286 → 360
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:38 → 114
    KH-I; K homology (KH) RNA-binding domain, type I

  21. XM_030245194.2 → XP_030101054.1  poly(rC)-binding protein 3 isoform X6

    Conserved Domains (2) summary
    cd00105
    Location:294 → 356
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  22. XM_006513917.1 → XP_006513980.1  poly(rC)-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006513980.1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  23. XM_006513918.1 → XP_006513981.1  poly(rC)-binding protein 3 isoform X1

    See identical proteins and their annotated locations for XP_006513981.1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  24. XM_017314038.1 → XP_017169527.1  poly(rC)-binding protein 3 isoform X5

    UniProtKB/Swiss-Prot
    P57722, Q8BSB0, Q8C544
    Related
    ENSMUSP00000129465.3, ENSMUST00000168465.9
    Conserved Domains (3) summary
    cd22519
    Location:125 → 203
    KH-I_PCBP3_rpt2; second type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cd22522
    Location:286 → 360
    KH-I_PCBP3_rpt3; third type I K homology (KH) RNA-binding domain found in poly(rC)-binding protein 3 (PCBP3) and similar proteins
    cl00098
    Location:38 → 114
    KH-I; K homology (KH) RNA-binding domain, type I

  25. XM_017314037.1 → XP_017169526.1  poly(rC)-binding protein 3 isoform X1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

  26. XM_017314036.2 → XP_017169525.1  poly(rC)-binding protein 3 isoform X1

    Conserved Domains (2) summary
    cd00105
    Location:318 → 380
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    cd02396
    Location:131 → 195
    PCBP_like_KH; K homology RNA-binding domain, PCBP_like. Members of this group possess KH domains in a tandem arrangement. Most members, similar to the poly(C) binding proteins (PCBPs) and Nova, containing three KH domains, with the first and second domains, which are ...

RNA

  1. XR_380424.4 RNA Sequence

  2. XR_380425.4 RNA Sequence

  3. XR_871722.3 RNA Sequence

  4. XR_004936231.1 RNA Sequence

  5. XR_004936230.1 RNA Sequence

  6. XR_003948755.1 RNA Sequence

  7. XR_380422.4 RNA Sequence

  8. XR_380423.4 RNA Sequence

  9. XR_001779566.2 RNA Sequence

  10. XR_871720.3 RNA Sequence

  11. XR_004936229.1 RNA Sequence

  12. XR_003948754.1 RNA Sequence

  13. XR_380420.4 RNA Sequence

  14. XR_871719.3 RNA Sequence

  15. XR_003948756.2 RNA Sequence

  16. XR_004936232.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P57722.3 GenPept UniProtKB/Swiss-Prot:P57722

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