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Fam184b family with sequence similarity 184, member B [ Mus musculus (house mouse) ]

Gene ID: 58227, updated on 21-Apr-2024

Summary

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Official Symbol
Fam184bprovided by MGI
Official Full Name
family with sequence similarity 184, member Bprovided by MGI
Primary source
MGI:MGI:2442958
See related
Ensembl:ENSMUSG00000015879 AllianceGenome:MGI:2442958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630031F12Rik
Summary
Is expressed in several structures, including gut; male reproductive gland or organ; nervous system; rib; and sensory organ. Orthologous to human FAM184B (family with sequence similarity 184 member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in frontal lobe adult (RPKM 1.7), cerebellum adult (RPKM 1.6) and 11 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 B3; 5 25.04 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (45687047..45796843, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (45529705..45639501, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6329 Neighboring gene STARR-seq mESC enhancer starr_12997 Neighboring gene leucine aminopeptidase 3 Neighboring gene mediator complex subunit 28 Neighboring gene STARR-seq mESC enhancer starr_13000 Neighboring gene STARR-seq mESC enhancer starr_13001 Neighboring gene STARR-seq mESC enhancer starr_13002 Neighboring gene STARR-seq mESC enhancer starr_13003 Neighboring gene STARR-seq mESC enhancer starr_13004 Neighboring gene RIKEN cDNA 9630001P10 gene Neighboring gene STARR-seq mESC enhancer starr_13005 Neighboring gene RIKEN cDNA 1600023N17 gene Neighboring gene STARR-positive B cell enhancer ABC_E1300 Neighboring gene DDB1 and CUL4 associated factor 16 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins. Nakayama M, et al. FASEB J, 2006 Aug. PMID 16807365
  2. An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. Ogaki S, et al. BMC Dev Biol, 2011 Mar 1. PMID 21362171, Free PMC Article
  3. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
  4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
  5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

See all (15) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (5)  1 citation
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Clone Names

  • KIAA1276

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM184B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021416.3 → NP_067391.3  protein FAM184B

    See identical proteins and their annotated locations for NP_067391.3

    Status: VALIDATED

    Source sequence(s)
    AB093291, BC056379, BY794536, CF539972
    Consensus CDS
    CCDS19276.1
    UniProtKB/Swiss-Prot
    Q0KK51, Q0KK56, Q76KB4, Q7TNB6, Q9JJG2
    Related
    ENSMUSP00000016023.8, ENSMUST00000016023.9
    Conserved Domains (3) summary
    COG1196
    Location:95 → 813
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15665
    Location:50 → 239
    FAM184; Family with sequence similarity 184, A and B
    cl19219
    Location:381 → 481
    DUF342; Protein of unknown function (DUF342)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    45687047..45796843 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0KK56.1 GenPept UniProtKB/Swiss-Prot:Q0KK56

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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