Golga7 golgin A7 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Golga7provided by MGI
Official Full Name: golgin A7provided by MGI
Primary source: MGI:MGI:1931029
See related: Ensembl:ENSMUSG00000015341 AllianceGenome:MGI:1931029
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: GCP16; HSPC041; GOLGA3AP1; C130038N16Rik
Summary: Predicted to be involved in establishment of protein localization to membrane; peptidyl-L-cysteine S-palmitoylation; and protein stabilization. Predicted to act upstream of or within Golgi to plasma membrane transport. Predicted to be located in Golgi membrane. Predicted to be intrinsic component of Golgi membrane. Predicted to be part of palmitoyltransferase complex. Predicted to be active in Golgi stack. Is expressed in several structures, including alimentary system; eye; genitourinary system; integumental system; and nervous system. Orthologous to human GOLGA7 (golgin A7). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E14 (RPKM 35.4), limb E14.5 (RPKM 33.1) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8 A2; 8 11.42 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (23731342..23747096, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (23241326..23258903, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1)
Targeted (2)
Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Process	Evidence Code	Pubs
involved_in Golgi to plasma membrane protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in Golgi to plasma membrane protein transport	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within Golgi to plasma membrane transport	ISO Inferred from Sequence Orthology more info
involved_in peptidyl-L-cysteine S-palmitoylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in peptidyl-L-cysteine S-palmitoylation	ISO Inferred from Sequence Orthology more info
involved_in protein stabilization	ISO Inferred from Sequence Orthology more info
involved_in protein targeting to membrane	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in Golgi apparatus	IEA Inferred from Electronic Annotation more info
located_in Golgi membrane	ISO Inferred from Sequence Orthology more info
is_active_in Golgi stack	IBA Inferred from Biological aspect of Ancestor more info
located_in Golgi stack	ISO Inferred from Sequence Orthology more info
located_in membrane	IEA Inferred from Electronic Annotation more info
part_of palmitoyltransferase complex	IBA Inferred from Biological aspect of Ancestor more info
part_of palmitoyltransferase complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: golgin subfamily A member 7

Names: golgi autoantigen, golgin subfamily a, 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001042484.1 → NP_001035949.1 golgin subfamily A member 7

See identical proteins and their annotated locations for NP_001035949.1

Status: VALIDATED

Description

Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.

Source sequence(s)

AC126038, AK150696, BY330336

Consensus CDS

CCDS40297.1

UniProtKB/Swiss-Prot

Q8BN18, Q91W53, Q9JJE0

Related

ENSMUSP00000062983.7, ENSMUST00000051094.9

Conserved Domains (1) summary

pfam10256
Location:12 → 124

Erf4; Golgin subfamily A member 7/ERF4 family
NM_020585.2 → NP_065610.2 golgin subfamily A member 7

See identical proteins and their annotated locations for NP_065610.2

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.

Source sequence(s)

AC126038, AK150696, BY330336

Consensus CDS

CCDS40297.1

UniProtKB/Swiss-Prot

Q8BN18, Q91W53, Q9JJE0

Related

ENSMUSP00000112935.2, ENSMUST00000121783.7

Conserved Domains (1) summary

pfam10256
Location:12 → 124

Erf4; Golgin subfamily A member 7/ERF4 family