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LINC00869 long intergenic non-protein coding RNA 869 [ Homo sapiens (human) ]

Gene ID: 57234, updated on 17-Mar-2024

Summary

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Official Symbol
LINC00869provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 869provided by HGNC
Primary source
HGNC:HGNC:29050
See related
Ensembl:ENSG00000291158 AllianceGenome:HGNC:29050
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM91A2
Summary
Predicted to be involved in intracellular protein transport and vesicle tethering to Golgi. Predicted to be active in cytoplasmic vesicle and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in spleen (RPKM 3.2), lymph node (RPKM 3.0) and 25 other tissues See more
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Genomic context

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Location:
1q21.2
Exon count:
10
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (149607012..149679523)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (148731162..148803659)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (149576161..149651107)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101060227 Neighboring gene tRNA-Asn (anticodon GTT) 25-1 Neighboring gene uncharacterized LOC124904410 Neighboring gene peptidylprolyl isomerase A like 4C Neighboring gene uncharacterized LOC124904409 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr1:147931672-147932203 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 1652 Neighboring gene RNA, variant U1 small nuclear 30 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:144301087-144301742 Neighboring gene protein FAM91A1-like Neighboring gene H3K4me1 hESC enhancer GRCh37_chr1:149287863-149288485 Neighboring gene RNA, U1 small nuclear 68, pseudogene Neighboring gene uncharacterized LOC644634

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Characterization of cDNA clones in size-fractionated cDNA libraries from human brain. Seki N, et al. DNA Res, 1997 Oct 31. PMID 9455484
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation.
    Title: LINC00869 Promotes Hepatocellular Carcinoma Metastasis via Protrusion Formation.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Other Names

  • family with sequence similarity 91, member A2

Clone Names

  • FLJ97060, FLJ99375, KIAA0493

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_111950.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) currently represents the longest transcript.
    Source sequence(s)
    AB007962, AC242842, CB217586
    Related
    ENST00000610578.4

  2. NR_111951.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
    Source sequence(s)
    AC242842, AC243772

  3. NR_111952.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
    Source sequence(s)
    AC242842, AC243772

  4. NR_111953.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9) lacks multiple 3' exons and contains an alternate 3' exon structure, resulting in a shorter transcript, compared to variant 6.
    Source sequence(s)
    AC242842, AC243772, BU602007

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    149607012..149679523
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    148731162..148803659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_046135.1: Suppressed sequence

    Description
    NR_046135.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

  2. NR_046136.1: Suppressed sequence

    Description
    NR_046136.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

  3. NR_046137.1: Suppressed sequence

    Description
    NR_046137.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

  4. NR_046138.1: Suppressed sequence

    Description
    NR_046138.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.

  5. NR_046139.1: Suppressed sequence

    Description
    NR_046139.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P0C866.1 GenPept UniProtKB/Swiss-Prot:P0C866

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.