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Zfp113 zinc finger protein 113 [ Mus musculus (house mouse) ]

Gene ID: 56314, updated on 5-Apr-2024

Summary

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Official Symbol
Zfp113provided by MGI
Official Full Name
zinc finger protein 113provided by MGI
Primary source
MGI:MGI:1929116
See related
Ensembl:ENSMUSG00000037007 AllianceGenome:MGI:1929116
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA4229; 4732456B05Rik
Summary
Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including early conceptus; enteric nervous system; genitourinary system; pancreas epithelium; and trunk somite. Orthologous to human ZNF3 (zinc finger protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 4.0), CNS E14 (RPKM 3.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
5 G2; 5 76.97 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (138137964..138154043, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (138139702..138155744, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene zinc finger with KRAB and SCAN domains 1 Neighboring gene STARR-positive B cell enhancer ABC_E8086 Neighboring gene zinc finger and SCAN domain containing 21 Neighboring gene STARR-positive B cell enhancer ABC_E4799 Neighboring gene STARR-positive B cell enhancer ABC_E9656 Neighboring gene COP9 signalosome subunit 6 Neighboring gene microRNA 25 Neighboring gene minichromosome maintenance complex component 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. Shannon M, et al. Genome Res, 2003 Jun. PMID 12743021, Free PMC Article
  2. Multiple genes encoding zinc finger domains are expressed in human T cells. Thiesen HJ. New Biol, 1990 Apr. PMID 2288909
  3. Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Memic F, et al. Gastroenterology, 2018 Feb. PMID 29031500, Free PMC Article
  4. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
  5. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

General gene information

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Markers

Homology

Clone Names

  • KIAA4229

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
zinc finger protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001429016.1 → NP_001415945.1  zinc finger protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC151719

  2. NM_019747.5 → NP_062721.2  zinc finger protein 3 isoform 1

    See identical proteins and their annotated locations for NP_062721.2

    Status: VALIDATED

    Source sequence(s)
    AC151719
    Consensus CDS
    CCDS19791.1
    UniProtKB/TrEMBL
    Q8C689
    Related
    ENSMUSP00000041796.9, ENSMUST00000049393.15
    Conserved Domains (6) summary
    smart00349
    Location:52 → 92
    KRAB; krueppel associated box
    COG5048
    Location:169 → 415
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:287 → 307
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:201 → 223
    zf-C2H2; Zinc finger, C2H2 type
    pfam01352
    Location:52 → 91
    KRAB; KRAB box
    pfam13465
    Location:243 → 268
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    138137964..138154043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036165327.1 → XP_036021220.1  zinc finger protein 3 isoform X1

    Conserved Domains (2) summary
    COG5048
    Location:89 → 335
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:207 → 227
    ZF_C2H2; C2H2 Zn finger [structural motif]
Nucleotide Protein Strain
Heading Accession and Version

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