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Mrpl37 mitochondrial ribosomal protein L37 [ Mus musculus (house mouse) ]

Gene ID: 56280, updated on 5-Mar-2024

Summary

Official Symbol
Mrpl37provided by MGI
Official Full Name
mitochondrial ribosomal protein L37provided by MGI
Primary source
MGI:MGI:1926268
See related
Ensembl:ENSMUSG00000028622 AllianceGenome:MGI:1926268
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Rpml2; MRP-L2; 2300004O14Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL37 (mitochondrial ribosomal protein L37). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in genital fat pad adult (RPKM 60.7), heart adult (RPKM 42.1) and 28 other tissues See more
Orthologs
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Genomic context

Location:
4 C7; 4 49.99 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (106913071..106924063, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (107055874..107066866, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6196 Neighboring gene predicted gene, 52672 Neighboring gene single-stranded DNA binding protein 3 Neighboring gene STARR-seq mESC enhancer starr_11016 Neighboring gene STARR-seq mESC enhancer starr_11017 Neighboring gene STARR-positive B cell enhancer ABC_E3500 Neighboring gene VISTA enhancer mm1261 Neighboring gene STARR-positive B cell enhancer ABC_E1035 Neighboring gene cytochrome b5 reductase-like Neighboring gene CUB domain containing protein 2 Neighboring gene predicted gene 12802 Neighboring gene transcription elongation factor A (SII) N-terminal and central domain containing 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables structural constituent of ribosome IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
involved_in translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
located_in mitochondrial ribosome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein mL37
Names
39S ribosomal protein L37, mitochondrial
L37mt
MRP-L37
ribosomal protein, mitochondrial, L2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025500.2NP_079776.1  large ribosomal subunit protein mL37 precursor

    See identical proteins and their annotated locations for NP_079776.1

    Status: VALIDATED

    Source sequence(s)
    AK161818, BY288824
    Consensus CDS
    CCDS18429.1
    UniProtKB/Swiss-Prot
    Q921S7
    Related
    ENSMUSP00000030365.6, ENSMUST00000030365.6
    Conserved Domains (1) summary
    pfam07147
    Location:271383
    PDCD9; Mitochondrial 28S ribosomal protein S30 (PDCD9)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    106913071..106924063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)