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Tmem131 transmembrane protein 131 [ Mus musculus (house mouse) ]

Gene ID: 56030, updated on 11-Apr-2024

Summary

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Official Symbol
Tmem131provided by MGI
Official Full Name
transmembrane protein 131provided by MGI
Primary source
MGI:MGI:1927110
See related
Ensembl:ENSMUSG00000026116 AllianceGenome:MGI:1927110
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Neg; RW1; CC28; YR-23; mKIAA0257; D1Bwg0491e; 2610524E03Rik
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in thymus primordium. Orthologous to human TMEM131 (transmembrane protein 131). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thymus adult (RPKM 16.9), colon adult (RPKM 15.5) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
1 B; 1 15.42 cM
Exon count:
41
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (36831270..36978714, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (36792189..36939614, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4933424G06 gene Neighboring gene predicted gene, 33533 Neighboring gene STARR-seq mESC enhancer starr_00648 Neighboring gene STARR-positive B cell enhancer ABC_E4309 Neighboring gene predicted gene, 18828 Neighboring gene zeta-chain (TCR) associated protein kinase Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:36854450-36854651 Neighboring gene STARR-seq mESC enhancer starr_00650 Neighboring gene STARR-seq mESC enhancer starr_00652 Neighboring gene STARR-seq mESC enhancer starr_00656 Neighboring gene STARR-seq mESC enhancer starr_00657 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:36976691-36976844 Neighboring gene STARR-seq mESC enhancer starr_00660 Neighboring gene ribosomal protein L12, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_00662 Neighboring gene STARR-seq mESC enhancer starr_00663 Neighboring gene STARR-seq mESC enhancer starr_00664 Neighboring gene STARR-positive B cell enhancer mm9_chr1:37057122-37057423 Neighboring gene nuclear encoded rRNA 5S 210

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Neg, a nerve growth factor-stimulated gene expressed by fetal neocortical neurons that is downregulated by ethanol. Miller MW, et al. J Comp Neurol, 2003 May 26. PMID 12687686
  2. Use of mRNA differential display to study the action of lymphocyte subsets in vivo and application to a murine model of herpes simplex virus infection. Tscharke DC, et al. Immunol Lett, 2000 Oct 3. PMID 10996388
  3. Sorting nexin-14, a gene expressed in motoneurons trapped by an in vitro preselection method. Carroll P, et al. Dev Dyn, 2001 Aug. PMID 11500980
  4. Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2002 Oct 31. PMID 12465718
  5. Tagging genes with cassette-exchange sites. Cobellis G, et al. Nucleic Acids Res, 2005 Mar 1. PMID 15741177, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (5) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
transmembrane protein 131

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018872.2 → NP_061360.2  transmembrane protein 131

    See identical proteins and their annotated locations for NP_061360.2

    Status: VALIDATED

    Source sequence(s)
    AB093221, AK012138, AK139317, BE956063, BU058584, CB518500, CD546146, CN533410
    Consensus CDS
    CCDS35538.1
    UniProtKB/Swiss-Prot
    O70472, Q8CHH3
    Related
    ENSMUSP00000027290.6, ENSMUST00000027290.12
    Conserved Domains (1) summary
    pfam12371
    Location:107 → 189
    TMEM131_like; Transmembrane protein 131-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    36831270..36978714 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036152473.1 → XP_036008366.1  transmembrane protein 131 isoform X3

    Conserved Domains (2) summary
    PTZ00449
    Location:1351 → 1595
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl13764
    Location:107 → 189
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

  2. XM_017321814.3 → XP_017177303.1  transmembrane protein 131 isoform X2

    Conserved Domains (2) summary
    PTZ00449
    Location:1351 → 1595
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl13764
    Location:107 → 189
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

  3. XM_006496150.4 → XP_006496213.1  transmembrane protein 131 isoform X1

    Conserved Domains (2) summary
    PTZ00449
    Location:1351 → 1648
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    cl13764
    Location:107 → 189
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin

RNA

  1. XR_004933922.1 RNA Sequence

  2. XR_004933916.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O70472.2 GenPept UniProtKB/Swiss-Prot:O70472

Gene LinkOut

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