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UBA6-DT UBA6 divergent transcript [ Homo sapiens (human) ]

Gene ID: 550112, updated on 26-Feb-2024

Summary

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Official Symbol
UBA6-DTprovided by HGNC
Official Full Name
UBA6 divergent transcriptprovided by HGNC
Primary source
HGNC:HGNC:49083
See related
Ensembl:ENSG00000248049 AllianceGenome:HGNC:49083
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
UBA6-AS1
Expression
Ubiquitous expression in thyroid (RPKM 4.5), prostate (RPKM 4.4) and 25 other tissues See more
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Genomic context

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Location:
4q13.2
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (67701278..67722505)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (71144388..71165615)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (68566996..68588223)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12077 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21597 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15462 Neighboring gene signal transducing adaptor family member 1 Neighboring gene ubiquitin like modifier activating enzyme 6 Neighboring gene small EDRK-rich factor 2-like Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15463 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15464 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15465 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 21598 Neighboring gene dynein, axonemal, assembly factor 5 pseudodgene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr4:68587217-68588416 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr4:68588737-68589525 Neighboring gene ST3GAL1 pseudogene 1 Neighboring gene tubulin alpha 4a pseudogene Neighboring gene small nucleolar RNA SNORA62/SNORA6 family Neighboring gene gonadotropin releasing hormone receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Amino acid restriction induces a long non-coding RNA UBA6-AS1 to regulate GCN2-mediated integrated stress response in breast cancer. Wu YZ, et al. FASEB J, 2022 Mar. PMID 35137449
  2. Long noncoding RNA UBA6-AS1 inhibits the malignancy of ovarian cancer cells via suppressing the decay of UBA6 mRNA. Wang Y, et al. Bioengineered, 2022 Jan. PMID 34951345, Free PMC Article
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. Kimura K, et al. Genome Res, 2006 Jan. PMID 16344560, Free PMC Article
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. Ota T, et al. Nat Genet, 2004 Jan. PMID 14702039
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Amino acid restriction induces a long non-coding RNA UBA6-AS1 to regulate GCN2-mediated integrated stress response in breast cancer.
    Title: Amino acid restriction induces a long non-coding RNA UBA6-AS1 to regulate GCN2-mediated integrated stress response in breast cancer.
Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

General gene information

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Markers

Other Names

  • UBA6 antisense RNA 1 (head to head)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_015439.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AK129519, BC043376, DA770515
    Related
    ENST00000506606.1

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

    Range
    67701278..67722505
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060928.1 Alternate T2T-CHM13v2.0

    Range
    71144388..71165615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Chemical Information
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