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BANP BTG3 associated nuclear protein [ Homo sapiens (human) ]

Gene ID: 54971, updated on 3-Apr-2024

Summary

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Official Symbol
BANPprovided by HGNC
Official Full Name
BTG3 associated nuclear proteinprovided by HGNC
Primary source
HGNC:HGNC:13450
See related
Ensembl:ENSG00000172530 MIM:611564; AllianceGenome:HGNC:13450
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BEND1; SMAR1; SMARBP1
Summary
This gene encodes a protein that binds to matrix attachment regions. The protein forms a complex with p53 and negatively regulates p53 transcription, and functions as a tumor suppressor and cell cycle regulator. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
Expression
Ubiquitous expression in testis (RPKM 1.3), spleen (RPKM 1.1) and 25 other tissues See more
Orthologs
mouse all
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Genomic context

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Location:
16q24.2
Exon count:
20
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (87949238..88077318)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (94021837..94148506)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (87982844..88110924)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:87931441-87932140 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11343 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11344 Neighboring gene carbonic anhydrase 5A Neighboring gene small EDRK-rich factor 1-like Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87979603-87980148 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11345 Neighboring gene H3K27ac hESC enhancer GRCh37_chr16:87984965-87985607 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11346 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:87990141-87991083 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88000587-88001090 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88008279-88008799 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88016725-88017317 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88033523-88034377 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88034378-88035231 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88039157-88039702 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88039703-88040246 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr16:88042893-88043606 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr16:88042179-88042892 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88046491-88047404 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88047405-88048317 Neighboring gene ReSE screen-validated silencer GRCh37_chr16:88058223-88058469 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88060746-88061316 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88064237-88064738 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88069223-88069723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88078499-88079000 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88096566-88097334 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:88098057-88098732 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88099409-88100084 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11348 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 11349 Neighboring gene uncharacterized LOC124903754 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88123859-88124486 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:88126373-88127000 Neighboring gene uncharacterized LOC400553 Neighboring gene zinc finger protein 469

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Structural insights into DNA recognition by the BEN domain of the transcription factor BANP. Liu K, et al. J Biol Chem, 2023 Jun. PMID 37086783, Free PMC Article
  2. SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin. Bhattacharya A, et al. Sci Signal, 2020 Oct 20. PMID 33082288
  3. SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression. Alam A, et al. Neoplasia, 2019 Oct. PMID 31422285, Free PMC Article
  4. Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer. Zhu M, et al. Biomed Pharmacother, 2017 Apr. PMID 28103507
  5. Gene regulation by SMAR1: Role in cellular homeostasis and cancer. Malonia SK, et al. Biochim Biophys Acta, 2011 Jan. PMID 20709157

See all (70) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
    Title: BANP Participates in the Chronic Intermittent Hypoxia-Induced Senescence of Vascular Endothelial Cells by Promoting P53 Phosphorylation and Nuclear Retention.
  2. Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells.
    Title: Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4 + T Cells.
  3. ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma.
    Title: ZNF471 Interacts with BANP to Reduce Tumour Malignancy by Inactivating PI3K/AKT/mTOR Signalling but is Frequently Silenced by Aberrant Promoter Methylation in Renal Cell Carcinoma.
  4. Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
    Title: Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.
  5. SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin.
    Title: SMAR1 repression by pluripotency factors and consequent chemoresistance in breast cancer stem-like cells is reversed by aspirin.
  6. BANP opens chromatin and activates CpG-island-regulated genes.
    Title: BANP opens chromatin and activates CpG-island-regulated genes.
  7. our observations establish that increased expression of SMAR1 in cancers can positively regulate MHC I surface expression thereby leading to higher chances of tumor regression and elimination of cancer cells.
    Title: SMAR1 favors immunosurveillance of cancer cells by modulating calnexin and MHC I expression.
  8. Cdc20 functions as an important negative regulator of SMAR1 in higher grades of cancer
    Title: Cdc20 directs proteasome-mediated degradation of the tumor suppressor SMAR1 in higher grades of cancer through the anaphase promoting complex.
  9. Dysregulated circ-BANP appears to have an important role in colorectal cancer cells.
    Title: Circular BANP, an upregulated circular RNA that modulates cell proliferation in colorectal cancer.
  10. results reveal the complex molecular mechanism underlying SMAR1-mediated signal-dependent and -independent regulation of alternative splicing via Sam68 deacetylation
    Title: Nuclear matrix-associated protein SMAR1 regulates alternative splicing via HDAC6-mediated deacetylation of Sam68.
Submit: New GeneRIF Correction See all GeneRIFs (30)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

EBI GWAS Catalog

Description
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
EBI GWAS Catalog
Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
EBI GWAS Catalog
New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.
EBI GWAS Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

HIV-1 interactions

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Protein interactions

Protein Gene Interaction Pubs
Tat tat SMAR1 recruits HDAC1-Sin3 corepressor complex to remodel chromatin structure at HIV-1 LTR. Overexpression of SMAR1 leads to reduction in LTR-mediated transcription in a Tat dependent and independent manner, resulting in a decreased virion production PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ10177, FLJ20538, DKFZp761H172

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell cycle IEA
Inferred from Electronic Annotation
more info
  
involved_in chromatin organization IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein localization to nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in nuclear body IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
  
located_in nucleoplasm TAS
Traceable Author Statement
more info
  

General protein information

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Preferred Names
protein BANP
Names
BEN domain-containing protein 1
scaffold/matrix-associated region-1-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_029918.1 RefSeqGene

    Range
    5003..130885
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001173539.2 → NP_001167010.1  protein BANP isoform c

    See identical proteins and their annotated locations for NP_001167010.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR, uses one alternate in-frame splices site, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (c) differs at two internal regions, compared to isoform g. Variants 3 and 9-11 all encode the same isoform (c).
    Source sequence(s)
    AK001039, AK125232, AK293472, AL157429
    Consensus CDS
    CCDS92204.1
    UniProtKB/TrEMBL
    B3KM38, B4DE54
    Related
    ENSP00000515015.1, ENST00000700483.1
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  2. NM_001173540.2 → NP_001167011.1  protein BANP isoform d

    See identical proteins and their annotated locations for NP_001167011.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) represents use of an alternate promoter and 5' UTR, uses three alternate in-frame splices sites, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (d) differs at four internal regions, compared to isoform g.
    Source sequence(s)
    AK001039, AK125232, AK297945, AL157429
    Consensus CDS
    CCDS54055.1
    UniProtKB/TrEMBL
    B3KM38
    Related
    ENSP00000487304.1, ENST00000626016.2
    Conserved Domains (1) summary
    smart01025
    Location:224 → 297
    BEN; The BEN domain is found in diverse animal proteins

  3. NM_001173541.2 → NP_001167012.1  protein BANP isoform e

    See identical proteins and their annotated locations for NP_001167012.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents use of an alternate promoter and 5' UTR, uses one alternate in-frame splices site, and lacks two alternate in-frame exons in the coding region, compared to variant 7. The resulting isoform (e) differs at three internal regions, compared to isoform g. Variants 5 and 12-14 all encode the same isoform (e).
    Source sequence(s)
    AK001039, AK297945, AK315089, AL157429
    Consensus CDS
    CCDS54053.1
    UniProtKB/TrEMBL
    B3KM38
    Related
    ENSP00000432508.1, ENST00000479780.6
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  4. NM_001173542.1 → NP_001167013.1  protein BANP isoform f

    See identical proteins and their annotated locations for NP_001167013.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices site, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (f) differs at three internal regions, compared to isoform g. Variants 6 and 15-17 all encode the same isoform (f).
    Source sequence(s)
    AK293472, AK297945, AK315535, AL157429
    Consensus CDS
    CCDS54052.1
    UniProtKB/TrEMBL
    A0A0S2Z5M2, B3KM38
    Related
    ENSP00000444352.1, ENST00000538234.5
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  5. NM_001173543.1 → NP_001167014.1  protein BANP isoform g

    See identical proteins and their annotated locations for NP_001167014.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) represents the longest transcript and encodes the longest isoform (g).
    Source sequence(s)
    AC127455, AK001039, AK094158, AK125232, AL157429
    Consensus CDS
    CCDS54054.1
    UniProtKB/Swiss-Prot
    A8MU25, A8MX25, B2RCF7, B4DNJ9, F5GZM0, Q8N9N5, Q96GJ7, Q9NWY1
    UniProtKB/TrEMBL
    B3KM38
    Related
    ENSP00000376902.1, ENST00000393207.5
    Conserved Domains (1) summary
    smart01025
    Location:249 → 322
    BEN; The BEN domain is found in diverse animal proteins

  6. NM_001384916.1 → NP_001371845.1  protein BANP isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8), as well as variant 1, encodes isoform a.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS42215.1
    UniProtKB/TrEMBL
    A0A0S2Z5C2, B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  7. NM_001384918.1 → NP_001371847.1  protein BANP isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9), as well as variants 3, 10, and 11, encodes isoform c.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS92204.1
    UniProtKB/TrEMBL
    B3KM38, B4DE54
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  8. NM_001384919.1 → NP_001371848.1  protein BANP isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10), as well as variants 3, 9, and 11, encodes isoform c.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS92204.1
    UniProtKB/TrEMBL
    B3KM38, B4DE54
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  9. NM_001384920.1 → NP_001371849.1  protein BANP isoform c

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11), as well as variants 3, 9, and 10, encodes isoform c.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS92204.1
    UniProtKB/TrEMBL
    B3KM38, B4DE54
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  10. NM_001384921.1 → NP_001371850.1  protein BANP isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (12), as well as variants 5, 13, and 14, encodes isoform e.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54053.1
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  11. NM_001384922.1 → NP_001371851.1  protein BANP isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (13), as well as variants 5, 12, and 14, encodes isoform e.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54053.1
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  12. NM_001384923.1 → NP_001371852.1  protein BANP isoform e

    Status: REVIEWED

    Description
    Transcript Variant: This variant (14), as well as variants 5, 12, and 13, encodes isoform e.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54053.1
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  13. NM_001384925.1 → NP_001371854.1  protein BANP isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (15), as well as variants 6, 16, and 17, encodes isoform f.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54052.1
    UniProtKB/TrEMBL
    A0A0S2Z5M2, B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  14. NM_001384926.1 → NP_001371855.1  protein BANP isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (16), as well as variants 6, 15, and 17, encodes isoform f.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54052.1
    UniProtKB/TrEMBL
    A0A0S2Z5M2, B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  15. NM_001384927.1 → NP_001371856.1  protein BANP isoform f

    Status: REVIEWED

    Description
    Transcript Variant: This variant (17), as well as variants 6, 15, and 16, encodes isoform f.
    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS54052.1
    UniProtKB/TrEMBL
    A0A0S2Z5M2, B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  16. NM_001384928.1 → NP_001371857.1  protein BANP isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variant 19, encodes isoform h.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:263 → 336
    BEN; The BEN domain is found in diverse animal proteins

  17. NM_001384929.1 → NP_001371858.1  protein BANP isoform h

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variant 18, encodes isoform h.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:263 → 336
    BEN; The BEN domain is found in diverse animal proteins

  18. NM_001384931.1 → NP_001371860.1  protein BANP isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variant 21, encodes isoform i.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:263 → 336
    BEN; The BEN domain is found in diverse animal proteins

  19. NM_001384935.1 → NP_001371864.1  protein BANP isoform i

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variant 20, encodes isoform i.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:263 → 336
    BEN; The BEN domain is found in diverse animal proteins

  20. NM_001384936.1 → NP_001371865.1  protein BANP isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variant 23, encodes isoform j.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:224 → 297
    BEN; The BEN domain is found in diverse animal proteins

  21. NM_001384937.1 → NP_001371866.1  protein BANP isoform j

    Status: REVIEWED

    Description
    Transcript Variant: This variant (23), as well as variant 22, encodes isoform j.
    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:224 → 297
    BEN; The BEN domain is found in diverse animal proteins

  22. NM_001384938.1 → NP_001371867.1  protein BANP isoform k

    Status: REVIEWED

    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:224 → 297
    BEN; The BEN domain is found in diverse animal proteins

  23. NM_001384939.1 → NP_001371868.1  protein BANP isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variant 26, encodes isoform l.
    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:154 → 227
    BEN; The BEN domain is found in diverse animal proteins

  24. NM_001384940.1 → NP_001371869.1  protein BANP isoform l

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variant 25, encodes isoform l.
    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:154 → 227
    BEN; The BEN domain is found in diverse animal proteins

  25. NM_001384941.1 → NP_001371870.1  protein BANP isoform m

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variant 28, encodes isoform m.
    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:154 → 227
    BEN; The BEN domain is found in diverse animal proteins

  26. NM_001384942.1 → NP_001371871.1  protein BANP isoform m

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variant 27, encodes isoform m.
    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:154 → 227
    BEN; The BEN domain is found in diverse animal proteins

  27. NM_001384943.1 → NP_001371872.1  protein BANP isoform n

    Status: REVIEWED

    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:115 → 188
    BEN; The BEN domain is found in diverse animal proteins

  28. NM_001384944.1 → NP_001371873.1  protein BANP isoform o

    Status: REVIEWED

    Source sequence(s)
    AC127455, AC134312
    Conserved Domains (1) summary
    smart01025
    Location:115 → 188
    BEN; The BEN domain is found in diverse animal proteins

  29. NM_001386991.1 → NP_001373920.1  protein BANP isoform p

    Status: REVIEWED

    Source sequence(s)
    AC127455, AC134312
    Consensus CDS
    CCDS92203.1
    UniProtKB/TrEMBL
    A0A804HKG3, B3KM38
    Related
    ENSP00000507916.1, ENST00000682872.1
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  30. NM_001386992.1 → NP_001373921.1  protein BANP isoform q

    Status: REVIEWED

    Source sequence(s)
    AC127455, AC134312
    UniProtKB/TrEMBL
    B3KM38
    Conserved Domains (1) summary
    smart01025
    Location:257 → 330
    BEN; The BEN domain is found in diverse animal proteins

  31. NM_001424170.1 → NP_001411099.1  protein BANP isoform c

    Status: REVIEWED

    Source sequence(s)
    CP068262
    UniProtKB/TrEMBL
    B4DE54

  32. NM_017869.4 → NP_060339.2  protein BANP isoform a

    See identical proteins and their annotated locations for NP_060339.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices sites, and lacks two alternate in-frame exons in the coding region, compared to variant 7. The resulting isoform (a) differs at four internal regions, compared to isoform g. Variants 1 and 8 both encode the same isoform (a).
    Source sequence(s)
    AK000545, AK001039, BC009424, CN289917, DA632793, T49823
    Consensus CDS
    CCDS42215.1
    UniProtKB/TrEMBL
    A0A0S2Z5C2, B3KM38
    Related
    ENSP00000347125.4, ENST00000355022.8
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

  33. NM_079837.3 → NP_524576.2  protein BANP isoform b

    See identical proteins and their annotated locations for NP_524576.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) represents use of an alternate promoter and 5' UTR, uses two alternate in-frame splices sites, and lacks one alternate in-frame exon in the coding region, compared to variant 7. The resulting isoform (b) differs at three internal regions, compared to isoform g.
    Source sequence(s)
    AK001039, AK125232, CN289917
    Consensus CDS
    CCDS10966.2
    UniProtKB/TrEMBL
    B3KM38
    Related
    ENSP00000376903.2, ENST00000393208.6
    Conserved Domains (1) summary
    smart01025
    Location:218 → 291
    BEN; The BEN domain is found in diverse animal proteins

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    87949238..88077318
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    94021837..94148506
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8N9N5.3 GenPept UniProtKB/Swiss-Prot:Q8N9N5

Gene LinkOut

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