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Pilrb2 paired immunoglobin-like type 2 receptor beta 2 [ Mus musculus (house mouse) ]

Gene ID: 545812, updated on 8-Feb-2024

Summary

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Official Symbol
Pilrb2provided by MGI
Official Full Name
paired immunoglobin-like type 2 receptor beta 2provided by MGI
Primary source
MGI:MGI:2450535
See related
Ensembl:ENSMUSG00000066682 AllianceGenome:MGI:2450535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
EG545812
Summary
Predicted to enable MHC class I protein binding activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human PILRA (paired immunoglobin like type 2 receptor alpha) and PILRB (paired immunoglobin like type 2 receptor beta). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in spleen adult (RPKM 6.5), liver E18 (RPKM 3.5) and 14 other tissues See more
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Genomic context

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See Pilrb2 in Genome Data Viewer
Location:
5 G2; 5 76.85 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (137864083..137870083, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (137865821..137871758, complement)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene zinc finger, CW type with PWWP domain 1 Neighboring gene STARR-seq mESC enhancer starr_14656 Neighboring gene paired immunoglobin-like type 2 receptor alpha Neighboring gene STARR-seq mESC enhancer starr_14658 Neighboring gene paired immunoglobin-like type 2 receptor beta 1 Neighboring gene predicted gene, 36551 Neighboring gene predicted gene 3103 Neighboring gene cytochrome P450, family 3, subfamily a, polypeptide 13

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative analysis of the paired immunoglobulin-like receptor (PILR) locus in six mammalian genomes: duplication, conversion, and the birth of new genes. Wilson MD, et al. Physiol Genomics, 2006 Nov 27. PMID 16926269
  2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
  4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
  5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables MHC class I protein binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
paired immunoglobulin-like type 2 receptor beta-2
Names
activating receptor PILR-beta-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024932.2 → NP_001020103.1  paired immunoglobulin-like type 2 receptor beta-2 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001020103.1

    Status: PROVISIONAL

    Source sequence(s)
    AK036467
    Consensus CDS
    CCDS51676.1
    UniProtKB/Swiss-Prot
    Q2YFS1
    Related
    ENSMUSP00000131233.2, ENSMUST00000164886.2
    Conserved Domains (1) summary
    cl11960
    Location:40 → 134
    Ig; Immunoglobulin domain

  2. NM_001384202.1 → NP_001371131.1  paired immunoglobulin-like type 2 receptor beta-2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AC125063
    UniProtKB/TrEMBL
    A0A0G2JF84
    Related
    ENSMUSP00000143064.2, ENSMUST00000196162.5
    Conserved Domains (2) summary
    cd00096
    Location:40 → 44
    Ig; Ig strand A [structural motif]
    cl11960
    Location:40 → 134
    Ig; Immunoglobulin domain

RNA

  1. NR_169051.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC125063

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    137864083..137870083 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_004942542.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q2YFS1.1 GenPept UniProtKB/Swiss-Prot:Q2YFS1

Gene LinkOut

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