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Or7c74 olfactory receptor family 7 subfamily C member 74 [ Mus musculus (house mouse) ]

Gene ID: 545417, updated on 8-Feb-2024

Summary

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Official Symbol
Or7c74provided by MGI
Official Full Name
olfactory receptor family 7 subfamily C member 74provided by MGI
Primary source
MGI:MGI:3030201
See related
Ensembl:ENSMUSG00000049094 AllianceGenome:MGI:3030201
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ORL1283; Olfr367; EG545417; MOR128-1; Olfr367-ps
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
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Genomic context

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Location:
2 B; 2 24.19 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (37156963..37161399)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (37266951..37271387)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene nucleoporin 50 pseudogene Neighboring gene olfactory receptor family 1 subfamily AF member 1 Neighboring gene STARR-seq mESC enhancer starr_04309 Neighboring gene STARR-seq mESC enhancer starr_04310 Neighboring gene predicted gene, 22306 Neighboring gene olfactory receptor family 5 subfamily C member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of potential regulatory motifs in odorant receptor genes by analysis of promoter sequences. Michaloski JS, et al. Genome Res, 2006 Sep. PMID 16902085, Free PMC Article
  2. Enhancer interaction networks as a means for singular olfactory receptor expression. Markenscoff-Papadimitriou E, et al. Cell, 2014 Oct 23. PMID 25417106, Free PMC Article
  3. The olfactory receptor gene superfamily of the mouse. Zhang X, et al. Nat Neurosci, 2002 Feb. PMID 11802173
  4. Different evolutionary processes shaped the mouse and human olfactory receptor gene families. Young JM, et al. Hum Mol Genet, 2002 Mar 1. PMID 11875048
  5. Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels. Young JM, et al. Genome Biol, 2003. PMID 14611657, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

General protein information

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Preferred Names
olfactory receptor family 7 subfamily C member 74
Names
GA_x6K02T2NLDC-33954853-33955794
olfactory receptor 367, pseudogene
olfactory receptor MOR128-1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081010.2 → NP_001074479.2  olfactory receptor family 7 subfamily C member 74 precursor

    Status: PROVISIONAL

    Source sequence(s)
    AL929572, DR065842
    UniProtKB/TrEMBL
    Q7TRY3
    Related
    ENSMUST00000143957.3
    Conserved Domains (2) summary
    pfam00001
    Location:8 → 257
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:1 → 272
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    37156963..37161399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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