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Anapc16 anaphase promoting complex subunit 16 [ Mus musculus (house mouse) ]

Gene ID: 52717, updated on 5-Mar-2024

Summary

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Official Symbol
Anapc16provided by MGI
Official Full Name
anaphase promoting complex subunit 16provided by MGI
Primary source
MGI:MGI:1289325
See related
Ensembl:ENSMUSG00000020107 AllianceGenome:MGI:1289325
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
APC16; D10Ertd641e; 2310005G07Rik
Summary
Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within cell division. Predicted to be located in chromosome, centromeric region; cytoplasm; and nucleus. Predicted to be part of anaphase-promoting complex. Predicted to be active in cytosol and kinetochore. Orthologous to human ANAPC16 (anaphase promoting complex subunit 16). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 22.8), limb E14.5 (RPKM 21.2) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 B4; 10 29.66 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (59823730..59838935, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (59987409..60003135, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40673 Neighboring gene STARR-seq mESC enhancer starr_26789 Neighboring gene STARR-seq mESC enhancer starr_26790 Neighboring gene STARR-seq mESC enhancer starr_26791 Neighboring gene STARR-seq mESC enhancer starr_26792 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:59432972-59433155 Neighboring gene DNA-damage-inducible transcript 4 Neighboring gene CapStarr-seq enhancer MGSCv37_chr10:59436913-59437130 Neighboring gene STARR-positive B cell enhancer mm9_chr10:59460432-59460732 Neighboring gene activating signal cointegrator 1 complex subunit 1 Neighboring gene STARR-positive B cell enhancer ABC_E2937 Neighboring gene predicted gene, 51801 Neighboring gene sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 Neighboring gene microRNA 6906

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. High-resolution genetic and physical mapping of modifier-of-deafwaddler (mdfw) and Waltzer (Cdh23v). Bryda EC, et al. Genomics, 2001 May 1. PMID 11350126
  2. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Ferguson CJ, et al. Mol Cell, 2022 Jan 6. PMID 34942119, Free PMC Article
  3. Transcriptome analysis of mouse stem cells and early embryos. Sharov AA, et al. PLoS Biol, 2003 Dec. PMID 14691545, Free PMC Article
  4. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
  5. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in protein ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein ubiquitination ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of anaphase-promoting complex ISO
Inferred from Sequence Orthology
more info
  
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
anaphase-promoting complex subunit 16
Names
cyclosome subunit 16

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347451.2 → NP_001334380.1  anaphase-promoting complex subunit 16 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC154040
    Consensus CDS
    CCDS83700.1
    UniProtKB/TrEMBL
    S4R2B6
    Related
    ENSMUSP00000020307.5, ENSMUST00000020307.11
    Conserved Domains (1) summary
    pfam17256
    Location:46 → 125
    ANAPC16; Anaphase Promoting Complex Subunit 16

  2. NM_025514.4 → NP_079790.1  anaphase-promoting complex subunit 16 isoform 1

    See identical proteins and their annotated locations for NP_079790.1

    Status: VALIDATED

    Source sequence(s)
    AC154040
    Consensus CDS
    CCDS23869.1
    UniProtKB/Swiss-Prot
    Q9CPV2
    Related
    ENSMUSP00000138112.2, ENSMUST00000182898.8
    Conserved Domains (1) summary
    pfam17256
    Location:27 → 106
    ANAPC16; Anaphase Promoting Complex Subunit 16

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    59823730..59838935 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CPV2.1 GenPept UniProtKB/Swiss-Prot:Q9CPV2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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