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Ccdc59 coiled-coil domain containing 59 [ Mus musculus (house mouse) ]

Gene ID: 52713, updated on 5-Mar-2024

Summary

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Official Symbol
Ccdc59provided by MGI
Official Full Name
coiled-coil domain containing 59provided by MGI
Primary source
MGI:MGI:1289302
See related
Ensembl:ENSMUSG00000019897 AllianceGenome:MGI:1289302
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D10Ertd718e; 2300004H16Rik
Summary
Predicted to be located in nucleus. Is expressed in early conceptus; embryo; extraembryonic component; oocyte; and primitive endoderm. Orthologous to human CCDC59 (coiled-coil domain containing 59). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 15.4), placenta adult (RPKM 12.8) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Ccdc59 in Genome Data Viewer
Location:
10 D1; 10 55.12 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (105677340..105683371)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (105841479..105847510)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr10:105012433-105012734 Neighboring gene predicted gene 15663 Neighboring gene STARR-seq mESC enhancer starr_27763 Neighboring gene STARR-seq mESC enhancer starr_27765 Neighboring gene methyltransferase like 25 Neighboring gene STARR-positive B cell enhancer ABC_E9803 Neighboring gene STARR-positive B cell enhancer ABC_E6919 Neighboring gene STARR-seq mESC enhancer starr_27766 Neighboring gene STARR-seq mESC enhancer starr_27767 Neighboring gene predicted gene, 25342 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Gineste C, et al. Neuromuscul Disord, 2013 Apr. PMID 23375831
  2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
thyroid transcription factor 1-associated protein 26
Names
TTF-1-associated protein 26
coiled-coil domain-containing protein 59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025602.3 → NP_079878.1  thyroid transcription factor 1-associated protein 26

    See identical proteins and their annotated locations for NP_079878.1

    Status: PROVISIONAL

    Source sequence(s)
    AC132471
    Consensus CDS
    CCDS24158.1
    UniProtKB/Swiss-Prot
    Q8BZ86, Q8R2N0, Q9CR69, Q9CV91
    Related
    ENSMUSP00000020049.9, ENSMUST00000020049.9
    Conserved Domains (2) summary
    pfam08524
    Location:138 → 239
    rRNA_processing; rRNA processing
    cl00489
    Location:164 → 211
    60KD_IMP; 60Kd inner membrane protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    105677340..105683371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8R2N0.2 GenPept UniProtKB/Swiss-Prot:Q8R2N0

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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