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Coa3 cytochrome C oxidase assembly factor 3 [ Mus musculus (house mouse) ]

Gene ID: 52469, updated on 11-Apr-2024

Summary

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Official Symbol
Coa3provided by MGI
Official Full Name
cytochrome C oxidase assembly factor 3provided by MGI
Primary source
MGI:MGI:1098757
See related
Ensembl:ENSMUSG00000017188 AllianceGenome:MGI:1098757
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ccdc56; HSPC009; D11Ertd99e; 1810033A19Rik
Summary
Predicted to be involved in mitochondrial cytochrome c oxidase assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Human ortholog(s) of this gene implicated in cytochrome-c oxidase deficiency disease. Orthologous to human COA3 (cytochrome c oxidase assembly factor 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 112.2), kidney adult (RPKM 101.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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Location:
11 D; 11 64.56 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101168796..101169774, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101277970..101278948, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:101114923-101115106 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:101115117-101115300 Neighboring gene vacuolar protein sorting 25 Neighboring gene WNK lysine deficient protein kinase 4 Neighboring gene cyclin N-terminal domain containing 1 Neighboring gene beclin 1, autophagy related Neighboring gene STARR-positive B cell enhancer ABC_E2370 Neighboring gene STARR-positive B cell enhancer ABC_E7066 Neighboring gene proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial cytochrome c oxidase assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial cytochrome c oxidase assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mitochondrial translation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
cytochrome c oxidase assembly factor 3 homolog, mitochondrial
Names
coiled-coil domain containing 56
coiled-coil domain-containing protein 56
cytochrome C oxidase assembly factor 3 homolog, mitochondrial
cytochrome c oxidase assembly protein 3 homolog, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026618.2 → NP_080894.1  cytochrome c oxidase assembly factor 3 homolog, mitochondrial

    See identical proteins and their annotated locations for NP_080894.1

    Status: PROVISIONAL

    Source sequence(s)
    AK019025
    Consensus CDS
    CCDS25460.1
    UniProtKB/Swiss-Prot
    A2A4J6, Q9D2R6
    UniProtKB/TrEMBL
    E9Q6W2
    Related
    ENSMUSP00000017332.4, ENSMUST00000017332.4
    Conserved Domains (1) summary
    pfam09813
    Location:9 → 106
    Coiled-coil_56; Coiled-coil domain-containing protein 56

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101168796..101169774 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D2R6.1 GenPept UniProtKB/Swiss-Prot:Q9D2R6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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