U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Rbm34 RNA binding motif protein 34 [ Mus musculus (house mouse) ]

Gene ID: 52202, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Official Symbol
Rbm34provided by MGI
Official Full Name
RNA binding motif protein 34provided by MGI
Primary source
MGI:MGI:1098653
See related
Ensembl:ENSMUSG00000033931 AllianceGenome:MGI:1098653
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
6330444B11; D8Ertd233e; 4930547K05Rik
Summary
Predicted to enable RNA binding activity. Predicted to be located in chromosome; nucleolus; and nucleoplasm. Is expressed in several structures, including cardiovascular system; gallbladder; genitourinary system; gut; and nervous system. Orthologous to human RBM34 (RNA binding motif protein 34). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 5.7), CNS E11.5 (RPKM 3.7) and 26 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
8 E2; 8 74.64 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (127673922..127697799, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (126947172..126971127, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene translocase of outer mitochondrial membrane 20 Neighboring gene predicted gene, 53208 Neighboring gene STARR-positive B cell enhancer ABC_E6707 Neighboring gene predicted gene, 26397 Neighboring gene STARR-seq mESC enhancer starr_23083 Neighboring gene STARR-positive B cell enhancer ABC_E6708 Neighboring gene predicted gene, 29688 Neighboring gene predicted gene, 38574

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. McKee AE, et al. BMC Dev Biol, 2005 Jul 20. PMID 16033648, Free PMC Article
  2. Transcription factor Foxp3 and its protein partners form a complex regulatory network. Rudra D, et al. Nat Immunol, 2012 Oct. PMID 22922362, Free PMC Article
  3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
  4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
enables molecular_function ND
No biological Data available
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables rRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in chromosome ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
RNA-binding protein 34

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001374800.1 → NP_001361729.1  RNA-binding protein 34 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC115706, AC119874
    Consensus CDS
    CCDS90487.1
    UniProtKB/TrEMBL
    A0A1D5RLR3
    Related
    ENSMUSP00000148473.2, ENSMUST00000212618.2
    Conserved Domains (2) summary
    cd12395
    Location:272 → 344
    RRM2_RBM34; RNA recognition motif 2 in RNA-binding protein 34 (RBM34) and similar proteins
    cl17169
    Location:189 → 260
    RRM_SF; RNA recognition motif (RRM) superfamily

  2. NM_172762.3 → NP_766350.2  RNA-binding protein 34 isoform 1

    See identical proteins and their annotated locations for NP_766350.2

    Status: VALIDATED

    Source sequence(s)
    AC119874, BC141278
    Consensus CDS
    CCDS22787.1
    UniProtKB/Swiss-Prot
    B2RUP0, Q8C5L7
    Related
    ENSMUSP00000048450.7, ENSMUST00000045994.8
    Conserved Domains (2) summary
    cd12394
    Location:189 → 280
    RRM1_RBM34; RNA recognition motif 1 in RNA-binding protein 34 (RBM34) and similar proteins
    cd12395
    Location:292 → 364
    RRM2_RBM34; RNA recognition motif 2 in RNA-binding protein 34 (RBM34) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    127673922..127697799 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8C5L7.2 GenPept UniProtKB/Swiss-Prot:Q8C5L7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous